Gadolinium powder — Safety Data Sheet — Thermo Fisher Scientific PAGE 1 SAFETY DATA SHEET Revision Date 22-Dec-2025 Revision Number 4 This safety data sheet was created pursuant to the requirements of: US OSHA Hazard Communication Standard 2024 (29 CFR 1910.1200) 1. Identification Product Name Gadolinium powder Cat No. : 45915 CAS No 7440-54-2 Synonyms No information available Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product use. Details of the supplier of the safety data sheet Company Thermo Fisher Scientific Chemicals, Inc. 30 Bond Street Ward Hill, MA 01835-8099 Tel: 800-343-0660 Fax: 800-322-4757 Emergency Telephone Number For information US call: 001-800-227-6701 / Europe call: +32 14 57 52 11 Emergency Number US:001-201-796-7100 / Europe: +32 14 57 52 99 CHEMTREC Tel. No. US:001-800-424-9300 / Europe:001-703-527-3887 2. Hazard(s) identification Classification This chemical is considered hazardous according to [US] OSHA (29 CFR 1910.1200, 2024) Flammable solids Category 1 Label Elements Signal Word Danger Hazard Statements Flammable solid ______________________________________________________________________________________________ Page 1 / 8 PAGE 2 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ Precautionary Statements Prevention Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking Ground and bond container and receiving equipment Use explosion-proof electrical/ventilating/lighting equipment Wear protective gloves/protective clothing/eye protection/face protection Fire In case of fire: Use CO2, dry chemical, or foam to extinguish Hazards not otherwise classified (HNOC) None identified Hazards classified under paragraph (d)(1)(ii) of 1910.1200 No information available 3. Composition/information on Ingredients Component CAS No Weight % Gadolinium 7440-54-2 <= 100 4. First-aid measures General Advice If symptoms persist, call a physician. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. Inhalation Remove to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. Ingestion Clean mouth with water and drink afterwards plenty of water. Get medical attention if symptoms occur. Most important symptoms and None reasonably foreseeable. effects Notes to Physician Treat symptomatically 5. Fire-fighting measures Unsuitable Extinguishing Media No information available Flash Point No information available Method - No information available Autoignition Temperature No information available Explosion Limits ______________________________________________________________________________________________ Page 2 / 8 PAGE 3 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ Upper No data available Lower No data available Sensitivity to Mechanical Impact No information available Sensitivity to Static Discharge No information available Specific Hazards Arising from the Chemical Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products None known. Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health Flammability Instability Physical hazards 0 2 0 N/A 6. Accidental release measures Personal Precautions Ensure adequate ventilation. Use personal protective equipment as required. Avoid dust formation. Environmental Precautions Should not be released into the environment. See Section 12 for additional Ecological Information. Methods for Containment and Clean Sweep up and shovel into suitable containers for disposal. Keep in suitable, closed Up containers for disposal. 7. Handling and Storage Handling Wear personal protective equipment/face protection. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation. Storage. Keep containers tightly closed in a dry, cool and well-ventilated place. 8. Exposure controls / personal protection Exposure Guidelines This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies. Engineering Measures Ensure adequate ventilation, especially in confined areas. Personal Protective Equipment Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin and body protection Wear appropriate protective gloves and clothing to prevent skin exposure. Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Hygiene Measures Handle in accordance with good industrial hygiene and safety practice. 9. Physical and chemical properties ______________________________________________________________________________________________ Page 3 / 8 PAGE 4 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ Appearance Physical State Solid Color Grey Odor No information available Odor Threshold No information available Property Values Remarks •Method Melting Point/Range 1312 °C / 2393.6 °F Softening Point No data available Boiling Point/Range 3273 °C / 5923.4 °F Flash Point No information available Method - No information available Flammability (liquid) Not applicable Solid Flammability (solid,gas) No information available Explosion Limits No data available Autoignition Temperature No data available Decomposition Temperature No data available pH Viscosity Not applicable Solid Water Solubility No information available Solubility in other solvents No information available Partition Coefficient (n-octanol/water) Vapor Pressure No data available Density / Specific Gravity No data available 7.898 @ 25°C Bulk Density No data available Vapor Density Not applicable Solid Particle characteristics No data available Other Information Molecular Formula Gd Molecular Weight 157.25 Flammable solids Burningrateorburningtime=≤5minutes Evaporation Rate Not applicable - Solid 10. Stability and reactivity Reactive Hazard None known, based on information available Stability Stable under normal conditions. Conditions to Avoid Incompatible products. Incompatible Materials Strong oxidizing agents Hazardous Decomposition Products None under normal use conditions Hazardous Polymerization Hazardous polymerization does not occur. Hazardous Reactions None under normal processing. 11. Toxicological information Information on expected route of exposure Inhalation Not an expected route of exposure. Ingestion May be harmful if swallowed. Eyes Avoid contact with eyes. Skin Avoid contact with skin. Toxicology data for the components ______________________________________________________________________________________________ Page 4 / 8 PAGE 5 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ Toxicologically Synergistic No information available Products (b) skin corrosion/irritation; No data available (c) serious eye damage/irritation; No data available (d) respiratory or skin sensitization; Respiratory No data available Skin No data available (e) germ cell mutagenicity; No data available (f) carcinogenicity; The table below indicates whether each agency has listed any ingredient as a carcinogen Component CAS No IARC NTP ACGIH OSHA Mexico Gadolinium 7440-54-2 Not listed Not listed Not listed Not listed Not listed (g) reproductive toxicity; No data available (h) STOT-single exposure; No data available (i) STOT-repeated exposure; No data available Target Organs No information available. (j) aspiration hazard; Not applicable Solid Symptoms / effects,both acute and No information available. delayed Other Adverse Effects The toxicological properties have not been fully investigated. Endocrine Disrupting Properties This product does not contain any known or suspected endocrine disruptors. 12. Ecological information Ecotoxicity Do not empty into drains. Persistence and Degradability No information available Bioaccumulation/ Accumulation No information available. Mobility No information available. 13. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a ______________________________________________________________________________________________ Page 5 / 8 PAGE 6 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. 14. Transport information DOT UN-No UN3089 Proper Shipping Name METAL POWDERS, FLAMMABLE, N.O.S. Technical Shipping Name Gadolinium powder Hazard Class 4.1 Packing Group II TDG UN-No UN3089 Proper Shipping Name Metal powder, flammable, n.o.s. Technical Shipping Name Gadolinium powder Hazard Class 4.1 Packing Group II IATA UN-No UN3089 Proper Shipping Name Metal powder, flammable, n.o.s. Technical Shipping Name Gadolinium powder Hazard Class 4.1 Packing Group II IMDG/IMO UN-No UN3089 Proper Shipping Name Metal powder, flammable, n.o.s. Technical Shipping Name Gadolinium powder Hazard Class 4.1 Packing Group II 15. Regulatory Information United States of America Inventory Component CAS No TSCA TSCA Inventory notification - TSCA - EPA Regulatory Active-Inactive Flags Gadolinium 7440-54-2 X ACTIVE - Legend: TSCA US EPA (TSCA) - Toxic Substances Control Act, (40 CFR Part 710) X - Listed '-' - Not Listed TSCA - Per 40 CFR 751, Regulation of Certain Chemical Not applicable Substances & Mixtures, Under TSCA Section 6(h) (PBT) TSCA 12(b) - Notices of Export Not applicable International Inventories Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Philippines (PICCS), Japan (ENCS), Japan (ISHL), Australia (AICS), China (IECSC), Korea (KECL). Component CAS No DSL NDSL EINECS PICCS ENCS ISHL AICS IECSC KECL Gadolinium 7440-54-2 - X 231-162-2 - X - - KE-05-0661 KECL - NIER number or KE number (http://ncis.nier.go.kr/en/main.do) U.S. Federal Regulations SARA 313 Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any ______________________________________________________________________________________________ Page 6 / 8 PAGE 7 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372 SARA 311/312 Hazard Categories Should this product meet EPCRA 311/312 Tier reporting criteria at 40 CFR 370, refer to Section 2 of this SDS for appropriate classifications. CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Not applicable Health Administration CERCLA This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state level pertaining to releases of this material. California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. State Right-to-Know Not applicable Regulations U.S. Department of Transportation Reportable Quantity (RQ): N DOT Marine Pollutant N DOT Severe Marine Pollutant N U.S. Department of Homeland This product does not contain any DHS chemicals. Security Other International Regulations Mexico - Grade No information available Authorisation/Restrictions according to EU REACH Not applicable Component CAS No REACH (1907/2006) - REACH (1907/2006) - REACH Regulation (EC Annex XIV - Substances Annex XVII - Restrictions 1907/2006) article 59 - Subject to Authorization on Certain Dangerous Candidate List of Substances Substances of Very High Concern (SVHC) Gadolinium 7440-54-2 - - - Safety, health and environmental regulations/legislation specific for the substance or mixture Component CAS No OECD HPV Persistent Organic Ozone Depletion Restriction of Pollutant Potential Hazardous Substances (RoHS) Gadolinium 7440-54-2 Not applicable Not applicable Not applicable Not applicable Contains component(s) that meet a 'definition' of per & poly fluoroalkyl substance (PFAS)? Not applicable ______________________________________________________________________________________________ Page 7 / 8 PAGE 8 Gadolinium powder Revision Date 22-Dec-2025 ______________________________________________________________________________________________ Other International Regulations Component CAS No Seveso III Directive Seveso III Directive Rotterdam Basel Convention (2012/18/EC) - (2012/18/EC) - Convention (PIC) (Hazardous Waste) Qualifying Quantities Qualifying Quantities for Major Accident for Safety Report Notification Requirements Gadolinium 7440-54-2 Not applicable Not applicable Not applicable Not applicable 16. Other Information Prepared By Health, Safety and Environmental Department Email: chem.techinfo@thermofisher.com www.thermofisher.com Revision Date 22-Dec-2025 Print Date 22-Dec-2025 Revision Summary UpdatedtotheU.S.DepartmentofLabor’sOccupationalSafetyandHealthAdministration (OSHA) which published its Final Rule in the Federal Register revising the Hazard Communication Standard (HCS/HazCom), 29 CFR 1910.1200 (2024) (HCS §1910.1200, 2024), May 20, 2024, effective July 19, 2024. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of SDS ______________________________________________________________________________________________ Page 8 / 8