Gadoxetate disodium — Safety Data Sheet — Ambeed PAGE 1 Ambeed, Inc. SAFETY DATA SHEET (A429813) 1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION 1.1 Product identifiers Product Name: Gadoxetate disodium CAS Number: 135326-22-6 Catalog Numbers: A429813 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses: For laboratory research purposes.Not for drug or household use. 1.3 Details of the supplier of the safety data sheet Ambeed, Inc. 3205 N WILKE RD, STE 3205-125, Arlington Hts, IL 60004, USA Tel: 1-352-323-3500 E-mail: sales@ambeed.com 1.4 Emergency telephone number Emergency phone (USA): 1-352-323-3500 Emergency phone (Canada): 1-800-535-5053 2. HAZARDS IDENTIFICATION 2.1 Classification of the substance or mixture GHS Classification in accordance with Hazardous Products Regulations (HPR) (SOR/2015-17) Acute toxicity, oral(Category 4) H302 Skin corrosion/irritation (Category 2) H315 Serious eye damage/eye irritation(Category 2A ) H319 Specific target organ toxicity, single exposure;Respiratory system(Category 3) H335 No Resource File 2.2 GHS Label elements, including precautionary statements Pictogra Signal word: Warning Hazard statement(s) H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary statement(s) P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 2.3 Other hazards Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 1 of 6 PAGE 2 Ambeed, Inc. SAFETY DATA SHEET (A429813) Additional precautionary phrases are located throughout the safety data sheet. 3. COMPOSITION, INFORMATION ON INGREDIENTS 3.1 Molecular Formula: C23H28GdN3Na2O11 Molecular Weight: 725.7115 Component Concentration Gadoxetate disodium CAS Number 135326-22-6 - 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Continue rinsing eyes during transport to hospital. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available 5. FIRE FIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media: alcohol-resistant foam, dry chemical or carbon dioxide Unsuitable extinguishing media: no data 5.2 Special hazards arising from the substance or mixture In combustion toxic fumes may form. 5.3 Advice for firefighters Wear self-contained breathing apparatus. Wear protective clothing to prevent contact with skin and eyes. Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 2 of 6 PAGE 3 Ambeed, Inc. SAFETY DATA SHEET (A429813) 6. ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Do not attempt to take action without suitable protective clothing. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains or river. Alert the neighbourhood to the presence of fumes or gas. 6.3 Methods and materials for containment and cleaning up Mix with sand or vermiculite. Sweep up and shovel. Transfer to a closable, labelled salvage container for disposal by an appropriate method. 6.4 Reference to other sections For disposal see section 13. 7. HANDLING AND STORAGE 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Wash hands thoroughly after handling. Ensure there is sufficient ventilation of the area. Normal measures for preventive fire protection. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated area. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Inert atmosphere,2-8°C 7.3 Specific end use(s) The end use(s) have not been fully determined. The substance is supplied for Research and Development purposes by professionals only. 8. EXPOSURE CONTROLS, PERSONAL PROTECTION 8.1 Control parameters Components with workplace control parameters Contains no substances with occupational exposure limit values. 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 3 of 6 PAGE 4 Ambeed, Inc. SAFETY DATA SHEET (A429813) Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Do not let product enter drains. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Solid Boiling Point No data available Melting Point No data available Odour No data available Odour Threshold No data available pH No data available Flash point No data available Evapouration rate No data available Vapour pressure No data available Vapor Density No data available Relative density No data available Solubility in water No data available Auto-ignition temperature No data available Decomposition temperature No data available Viscosity No Data No data available Explosive properties No data available Oxidizing properties No data available 10. STABILITY AND REACTIVITY 10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 4 of 6 PAGE 5 Ambeed, Inc. SAFETY DATA SHEET (A429813) No data available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products Carbon monoxide, carbon dioxide, nitrogen oxides, metallic oxides. 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute Toxicity No data available Skin corrosion/irritation No data available Serious eye Damage/irritation No data available Respiratory or skin sensitisation No data available Germ Cell mutagenicity No data available Carcinogenicity No data available Reproductive toxicity No data available STOT-single exposure No data available STOT-repeated exposure No data available Aspiration hazard No data available 11.2 Additional To the best of our knowledge the acute and chronic toxicity of this substance is not fully known. No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH 12. ECOLOGICAL INFORMATION 12.1 Toxicity No data available. 12.2 Persistence and degradability No data available. 12.3 Bioaccumulative potential No data available. 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment No data available 12.6 Other adverse effects No data available 13. DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Disposal Operations Consult state, local or national regulations for proper disposal. Hand over to authorised disposal company as hazardous waste. Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 5 of 6 PAGE 6 Ambeed, Inc. SAFETY DATA SHEET (A429813) Disposal of Packaging Disposal must be made according to official regulations. 14. TRANSPORT INFORMATION DOT (US) Classed non-hazardous for shipping. IMDG Classed non-hazardous for shipping. IATA Classed non-hazardous for shipping. 15. REGULATORY INFORMATION Safety, health and environmental and national regulations: Product is not subject to any additional regulations or provisions California Proposition 65 Not listed on California’s listing of known or potential carcinogens. Safety Assessment No Chemical Safety Assessment 16. OTHER INFORMATION The reference company name of written contents Company: Ambeed, Inc. Tel: 1-352-323-3500 Fax:1-352-323-3500 E-mail: sales@ambeed.com Address: 3205 N WILKE RD, STE 3205-125, Arlington Hts, IL 60004, USA This SDS was prepared sincerely on the basis of the information we could obtained, however, any warranty shall not be given regarding the data contained and the assessment of hazards and toxicity. Prior to use, please investigate not only the hazards and toxicity information but also the laws and regulations of the organization, area and country where the products are to be used, which shall be given the first priority.products are supposed to be used promptly after purchase in consideration of safety. Some new information or amendments may be added afterwards. If the products are to be used far behind the expected time of use or you have any questions, please feel free to contact us. The stated cautions are for normal handling only. In case of special handling, sufficient care should be taken, in addition to the safety measures suitable for the situation. All chemical products should be treated with the recognition of "having unknown hazards and toxicity", which differ greatly depending on the conditions and handling when in use and/or the conditions and duration of storage. The products must be handled only by those who are familiar with specialized knowledge and have experience or under the guidance of those specialists throughout use from opening to storage and disposal. Safe usage conditions shall be set up on each user's own responsibility. Revision Date 04/23/2020 Print Date 12/16/2022 Product Url: www.ambeed.com/products/135326-22-6.html For Laboratory Use Only ! 1-352-323-3500 1-352-323-3500 sales@ambeed.com www.ambeed.com 3205 N WILKE Rd, STE 3205-125, Arlington Hts, IL 60004, USA Page 6 of 6