Zirconium-92 SDS

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 1/9

Section 1: Identification of the Substance/混合物 and of the Company/Undertaking

Product Identifier: Identification as on the label/商品名： Zirconium Dioxide, Enriched in Zirconium. 分子量: 123.22 化学式: ZrO 2 別名: Zirconia. 詳細 of the supplier of the 安全データシート: Neonest AB Storgatan 70C, Solna SE-17152 Sweden Contact details: +46-76-219-9731 24-hour Emergency Contact: Swedish Poisons Centre 電話番号: 112 - Ask for Poisons Information, 112 – begär Giftinformation . Other International Contacts: CHEMTREC 24-hour: +1-703-741-5500 (US + Worldwide) NHS: 111 (UK) Charite: +49 30 450 531 000 (Netherlands) INTCF: +34 917689800 (Spain) CapTv: +33 1 40 05 48 48 (フランス)

Section 2: Hazards Identification

Classification of the substances or mixture: The mixture is classified according to: Regulation EC 1272/2008 [EU-GHS/CLP] Hazard classes/Hazard categories: Hazard statement: Not classified as hazardous. None required. Label elements: Hazard pictograms: Not required. Signal Words: Not required. Hazard Statements: Not required. Precautionary Statements: None. Other hazards: None known.

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 2/9

Section 3: 組成/Information on Ingredients

Substance/混合物: Substance. Ingredients: Substance name (IUPAC/EC) CAS - No. Molecular weight Concentration % by weight Classification EC1272/2008 EC - No. Zirconium dioxide 1314-23-4 123.22 >99% Not Classified. 215-227-2 For explanation of abbreviations see Section 16.

Section 4: First - Aid Measures

説明 of first aid measures: In case of inhalation: If breathed in, move person into fresh air. If not breathing, give artificial respiration Consult a physician. In case of skin contact: Wash off with soap and plenty of water. Consult a physician. In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. In case of ingestion: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed: Inhalation: May be harmful if inhaled; causes respiratory tract irritation. Eyes: Causes eye irritation. Skin contact: May be harmful if absorbed through skin; causes skin irritation. Ingestion: May be harmful if swallowed. Indication of any immediate medical attention and special treatment needed: Treat symptomatically. Show this safety data sheet to a physician or emergency room.

Section 5: Fire - Fighting Measures

Extinguisher media: Suitable extinguisher media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Unsuitable extinguishing media: None known. Special hazards arising from the mixture: Zirconium oxides. Advice for fire-fighters: Wear self-contained breathing apparatus for firefighting if necessary. Further information: Standard procedure for chemical fires. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Personal precautions: Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 3/9 Environmental precautions: Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. Local authorities should be advised if significant spillages cannot be contained. Methods for containment and cleaning up: Methods for cleaning up: Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal. Reference to other sections: Treat recovered material as described in the section "Disposal considerations".

Section 7: Handli ng and Storage

Precautions for safe handling: Advice on safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection. Hygiene measures: Do not eat, drink or smoke when using this product. Conditions for safe storage, including incompatibilities: Requirements for storage areas and containers: Keep container tightly closed in a dry and well-ventilated place.

Section 8: Exposure Controls/ Personal Protection

Control parameters: Occupational exposure limits: Components CAS-No. Value Control parameters Update Basis Zirconium dioxide 1314-23-4 TWA 5 mg/m 3 1993-06-30 USA. Occupational Exposure Limits (OSHA)-Table Z- 1 Limits for Air Contaminants TWA 5 mg/m 3 1989-03-01 USA.OSHA-TABLE Z-1 Limits for Air Contaminants - 1910.1000 TWA 10 mg/m 3 1989-03-01 USA.OSHA-TABLE Z-1 Limits for Air Contaminants - 1910.1000 TWA 5 mg/m 3 1996-05-18 USA. ACGIH Threshold Limit Values (TLV) Remarks Not classifiable as a human carcinogen: Agents which cause concern that they could be carcinogenic for humans but which cannot be assessed conclusively because of a lack of data. In vitro or animal studies do not provide indications of carcinogenicity which are sufficient to classify the agent into one of the other categories. 1996 Adoption Refers to Appendix A -- Carcinogens STEL 10 mg/m 3 1996-05-18 USA. ACGIH Threshold Limit Values (TLV) Not classifiable as a human carcinogen: Agents which cause concern that they could be carcinogenic for humans but which cannot be assessed conclusively because of a lack of data. In vitro or animal studies do not provide indications of carcinogenicity which are sufficient to classify the agent into one

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 4/9 of the other categories. 1996 Adoption Refers to Appendix A -- Carcinogens. Exposure controls: Appropriate engineering controls: Safety shower and eye bath. Mechanical exhaust required. Individual protection measures, such as personal protective equipment: Eye/face protection: Safety glasses with side-shields conforming to EN166. Hand protection: Use chemical resistant gloves. Examples of preferred glove barrier materials include: Butyl rubber, Neoprene, Nitrile/butadiene rubber, Polyethylene, Ethyl vinyl alcohol laminate, polyvinyl alcohol, Polyvinyl chloride. Body protection: Choose body protection according to the amount and concentration of the dangerous substance at the work place. Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Section 9: Physica l and Chemical Properties

Information on basic physical and chemical properties Appearance (form): Solid (powder). Colour: White. Odour: No data available. Odour threshold: No data available. Molecular Weight: 123.22 pH (concentration): No data available. Melting point/range (° C): 2700 °C Boiling point/range (° C): 5000 °C Freezing point (°C): No data available. Flash point (° C): No data available. Evaporation rate: No data available. Flammability (solid, gas): No data available. Ignition temperature (° C): No data available. Upper/lower flammability/explosive limits: No data available. Vapour pressure (20 ° C): No data available Vapour density: No data available. Relative densi ty (25 ° C): 5.89 g/mL Water solubility (g/L ) at 20 ° C: No data available. n-Octanol/Water partition coefficient : No data available. Auto-ignition temperature: No data available. Decomposition temperature: No data available. Viscosity, dynamic (mPa s): No data available. Explosive properties: The substance or mixture is not classified as explosive. Oxidising properties: The substance or mixture is not classified as oxidizing.

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 5/9

Section 10: Stability and Reactivity

Reactivity: No dangerous reaction known under conditions of normal use. Chemical stability: Stable under normal conditions. Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use. Conditions to avoid: None known . Incompatible materials: Strong oxidizing agents, strong acids. Hazardous decomposition products: Hazardous decomposition products formed under fire conditions: Zirconium oxides.

Section 11: Toxicological Information

Information on toxicological effects: Not classified based on available information. Classification according to GHS (1272/2008/EG, CLP) Skin corrosion/irritation: Not classified based on available information. Serious eye damage/eye irritation: Not classified based on available information. Respiratory or skin sensitisation: Not classified based on available information. Germ cell mutagenicity: Not classified based on available information. Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity: Not classified based on available information. Specific target organ toxicity – single exposure (STOT): Not classified based on available information. Specific target organ toxicity (STOT) – repeated exposure: Not classified based on available information. Aspiration toxicity: Not classified based on available information.

Section 12: Ecological Information

Toxicity: No data available. Persistence and degradability: No data available. Bioaccumulative potential: No data available.

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 6/9 Mobility in soil: No data available. 検索結果 of PBT& vPvB assessment: Not relevant. Other adverse effects: No data available.

Section 13: Disposal Considerations

Waste treatment methods: Contact a licensed professional waste disposal service to dispose of this material. Observe all local and national environmental regulations.

Section 14: Transport Information

UN number: Not regulated as a dangerous good. UN proper shipping name: Not regulated as a dangerous good. Transport hazard class(es): Not regulated as a dangerous good. Packing group: Not regulated as a dangerous good. Environmental hazards: Not regulated as a dangerous good. Special precautions for user: Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR. Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable.

Section 15: Regulatory Information

EU regulations: Regulation (EC) No. 1005/2009 on substances that deplete the ozone layer, Annex I and II, as amended Not listed. Regulation (EC) No. 850/2004 on persistent organic pollutants, Annex I Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 1 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 2 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 3 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex V as amended Not listed. Regulation (EC) No. 166/2006 Annex II Pollutant Release and Transfer Registry Not listed. Regulation (EC) No. 1907/2006, REACH Article 59(10) Candidate List as currently published by ECHA Not listed. Authorisations: Regulation (EC) No. 1907/2006, REACH Annex XIV Substances subject to authorization, as amended Not listed. Restrictions on use:

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 7/9 Regulation (EC) No. 1907/2006 Annex XVII Substances subject to restriction on marketing and use Not regulated. Regulation (EC) No. 1907/2006, REACH Annex XVII Substances subject to restriction on marketing and use as amended Not listed. Directive 2004/37/EC on the protection of workers from the risks related to exposure to carcinogens and mutagens at work Not regulated. Directive 92/85/EEC: on the safety and health of pregnant workers and workers who have recently given birth or are breastfeeding. Not regulated. Other EU regulations: Directive 2012/18/EU on major accident hazards involving dangerous substances Not listed. Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Always applicable. Directive 94/33/EC on the protection of young people at work Not listed. Other regulations: The product is classified and labelled in accordance with EC directives or respective national laws. This 安全データシート complies with the requirements of Regulation (EC) No 1907/2006, as amended. OSHA Hazards: Irritant. SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III,

Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards: Acute Health Hazard. Massachusetts Right to Know Components: Zirconium dioxide / CAS No. 1314-23-4 / 改訂版 Date 1993-04-24 Pennsylvania Right to Know Components: Zirconium dioxide / CAS No. 1314-23-4 / 改訂版 Date 1993-04-24 New Jersey Right to Know Components: Zirconium dioxide / CAS No. 1314-23-4 / 改訂版 Date 1993-04-24 California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm. National regulations: Follow national regulation for work with chemical agents. Chemical safety assessment: No Chemical Safety Assessment has been carried out.

Section 16: Other Information

List of abbreviations: ACGIH American Conference of Governmental Industrial Hygienists ADR European Agreement Concerning the International Carriage of Dangerous Goods by Road ALARA As Low As Is Reasonably Achievable AMU Atomic Mass Unit ANSI American National Standards Institute BLS Basic Life Support CAM Continuous Air Monitor

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 8/9 CAS Chemical Abstracts Service (division of the American Chemical Society) CEN European Committee for Standardization CERCLA Comprehensive Environmental Response Compensation and Liability Act CLP Classification, Labelling and Packaging (European Union) CPR Controlled Products Regulations (Canada) CWA Clean Water Act (USA) DAC Derived Air Concentration (USA) DOE 米国 Department of Energy (USA) DOT 米国 Department of Transportation (USA) DSL Domestic Substances List (Canada) EC50 Half Maximal Effective Concentration EINECS European Inventory of Existing Commercial Chemical Substances EHS Environmentally Hazardous Substance ELINCS European List of Notified Chemical Substances EMS Emergency Response Procedures for Ships Carrying Dangerous Goods EPA Environmental Protection Agency (USA) EPCRA Emergency Planning and Community Right-To-Know Act (EPCRA) of 1986 GHS Globally Harmonized System HMIS Hazardous 材料 Identification System (USA) IARC International Agency for Research on Cancer IATA International Air Transport Association IBC Intermediate Bulk Containers ICAO International Civil Aviation Organization IDLH Immediately Dangerous to Life or Health IMDG International Maritime Code for Dangerous Goods LC50 Lethal concentration, 50 percent LD50 Lethal dose, 50 percent LDLO Lethal Dose Low LOEC Lowest-Observed-Effective Concentration MARPOL International Convention for the Prevention of Pollution from Ships MSHA Mine Safety and Health Administration (USA) NCRP National Council on Radiation Protection & Measurements (USA) NDSL Non-Domestic Substances List (Canada) NFPA National Fire Protection Association (USA) NIOSH National Institute for Occupational Safety and Health (USA) NOEC No Observed Effect Concentration N.O.S. Not Otherwise Specified NRC Nuclear Regulatory Commission (USA) NTP National Toxicology Program (USA) OSHA Occupational Safety and Health Administration (USA) PBT Persistent Bioaccumulative and Toxic Chemical PEL Permissible Exposure Limit PIH Poisonous by Inhalation Hazard RCRA Resource Conservation and Recovery Act (USA) RCT Radiation Control Technician REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (Europe) RID Regulations Concerning the International Transport of Dangerous Goods by Rail

安全データシート for Zirconium Oxide, Enriched Zirconium Oxide According to ISO 11014:2010 First Print Date: 5-Mar-2015 改訂版 Date: 31-Aug-2019 Version: 1.1.1. 安全データシート (SDS) for Zirconium Dioxide, Enriched in Zirconium https://www.buyisotope.com ページ 9/9 RTECS Registry of Toxic Effects of Chemical Substances SARA Superfund Amendments and Reauthorization Act (USA) TDG Transportation of Dangerous Goods (Canada) TIH Toxic by Inhalation Hazard TLV Threshold Limit Value TPQ Threshold Planning Quantity TSCA Toxic Substances Control Act TWA Time Weighted Average UN United Nations (Number) VOC Volatile Organic 化合物 vPvB Very Persistent Very Bioaccumulative Chemical WGK Wassergefährdungsklassen (ドイツ: Water Hazard Classes) WHMIS Workplace Hazardous 材料 Information System References: 情報なし. 全文 of any H-statements not written out in full under Sections 2 to 15: None. 改訂版 information: None. Training information: Follow training instructions when handling this material. Further Information: The information provided in this 安全データシート is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.