セリウム (Ce) 標準液 SRM 3110 SDS

Date of Issue: 2016年12月8日 SAFETY DATA SHEET

1. SUBSTANCE AND SOURCE IDENTIFICATION Product Identifier SRM Number: 3110 SRM Name: Cerium (Ce) 標準液 Other Means of Identification: Not applicable. おすすめ Use of This Material and Restrictions of Use This Standard Reference Material (SRM) is intended for use as a primary calibration standard for the quantitative determination of cerium. A unit of SRM 3110 consists of five 10 mL sealed borosilicate glass ampoules of an acidified aqueous solution prepared gravimetrically to contain a known mass fraction of cerium. The solution contains nitric acid at a volume fraction of approximately 16 %. Company Information 米国国立標準技術研究所 標準物質プログラム 100 Bureau Drive, Stop 2300 Gaithersburg, Maryland 20899-2300

Telephone: 301-975-2200 Emergency Telephone ChemTrec: FAX: 301-948-3730 1-800-424-9300 (North America) E-mail: SRMMSDS@nist.gov +1-703-527-3887 (International) ウェブサイト: http://www.nist.gov/srm

2. HAZARDS IDENTIFICATION

Classification Physical Hazard: Not classified. Health Hazard: Skin Corrosion/Irritation Category 1B Serious Eye Damage/Eye Irritation Category 1

Label 元素s Symbol

Signal Word DANGER Hazard Statement(s) H314 Causes severe skin burns and eye damage. Precautionary Statement(s) P260 Do not breathe fumes, mists, vapors, or spray. P264 Wash hands thoroughly after handling. P280 Wear protective gloves, protective clothing, and eye protection. P301+P330+P331 If swallowed: Rinse mouth. Do NOT induce vomiting. P303+P361+P353 If on skin (or hair): Remove immediately all contaminated clothing. Rinse skin with water. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a doctor. P363 Wash contaminated clothing before reuse.

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P405 Store locked up. P501 Dispose of container and contents according to local regulations. Hazards Not Otherwise Classified: Not applicable. Ingredients(s) with Unknown Acute Toxicity: Not applicable.

3. COMPOSITION AND INFORMATION ON HAZARDOUS INGREDIENTS

物質：硝酸溶液中のセリウム Other Designations: Nitric acid (aqua fortis; hydrogen nitrate; azotic acid; engraver’s acid) Cerium nitrate [Cerous nitrate; cerium (III) nitrate; nitric acid, cerium (III) salt] NOTE: Cerium in nitric acid solution forms a solvated cerium nitrate salt. Components are listed in compliance with OSHA’s 29 CFR 1910.1200; for the actual values see the NIST Certificate of Analysis. Hazardous Component(s) CAS番号 EC Number Nominal Mass Concentration (EINECS) (%) Nitric acid 7697-37-2 231-714-2 <20 Cerium nitrate 10108-73-3 233-297-2 2.3

Non-Hazardous Component(s) Water 7732-18-5 231-791-2 >77

4. FIRST AID MEASURES

説明 of First Aid Measures: Inhalation: If adverse effects occur, remove to uncontaminated area. If not breathing, give artificial respiration or oxygen by qualified personnel. Seek immediate medical attention. Skin Contact: Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get immediate medical attention. Thoroughly clean and dry contaminated clothing before reuse. Destroy contaminated shoes. Eye Contact: Immediately flush eyes, including under the eyelids with copious amounts of water for at least 15 minutes. Seek immediate medical attention. Ingestion: Contact a poison control center immediately for instructions. Do not induce vomiting. Give water to rinse out mouth. Never give liquids to a person with reduced awareness or becoming unconscious. If vomiting occurs, keep head lower than hips to prevent aspiration. If not breathing, give artificial respiration by qualified personnel. Seek immediate medical attention. Most Important Symptoms/Effects, Acute and Delayed: Acid burns to skin, eyes, and lungs. Indication of any immediate medical attention and special treatment needed, if necessary: If any of the above symptoms are present, seek immediate medical attention.

5. FIRE FIGHTING MEASURES

Fire and Explosion Hazards: Negligible fire hazard. See Section 9, “Physical and Chemical Properties” for flammability properties. Extinguishing Media: Suitable: Use extinguishing media appropriate to the surrounding fire. Unsuitable: None listed. Specific Hazards Arising from the Chemical: Thermal decomposition will produce oxides of nitrogen and cerium.

Special Protective Equipment and Precautions for Fire-Fighters: Avoid inhalation of material or combustion byproducts. Wear full protective clothing and NIOSH approved self-contained breathing apparatus (SCBA).

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NFPA Ratings (0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe) Health = 3 Fire = 0 Reactivity = 0

6. ACCIDENTAL RELEASE MEASURES

Personal Precautions, Protective Equipment and Emergency Procedures: Immediately contact emergency personnel. Keep unnecessary personnel away. Use suitable protective equipment; see Section 8, “Exposure Controls and Personal Protection”. Methods and 材料 for Containment and Clean up: Do not touch spilled material. Notify safety personnel of spills. Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. Isolate hazard area and deny entry.

7. HANDLING AND STORAGE

Safe Handling Precautions: See Section 8, “Exposure Controls and Personal Protection”. Storage: Store and handling in accordance with all current regulations and standards. Keep separated from incompatible substances (see Section 10, “Stability and Reactivity”).

8. EXPOSURE CONTROLS AND PERSONAL PROTECTION

Exposure Limits Component: Nitric acid: NIOSH (REL): 5 mg/m3 (2 ppm) TWA 10 mg/m3 (4 ppm) STEL 65 mg/m3 (25 ppm) IDLH ACGIH (TLV): 5 mg/m3 (2 ppm) TWA 10 mg/m3 (4 ppm) STEL OSHA (PEL): 5 mg/m3 (2 ppm) TWA Component: Cerium nitrate No occupational exposure limits established. Engineering Controls: Provide local exhaust or process enclosure ventilation system. Ensure compliance with applicable exposure limits. Personal Protection: In accordance with OSHA 29 CFR 1910.132, subpart I, wear appropriate Personal Protective Equipment (PPE) to minimize exposure to this material. Respiratory Protection: If workplace conditions warrant a respirator, a respiratory protection program that meets OSHA 29CFR 1910.134 must be followed. Refer to NIOSH 42 CFR 84 for applicable certified respirators. Eye/Face Protection: Wear splash resistant safety goggles with a face shield. An eyewash station should be readily available near areas of use. Skin and Body Protection: Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Chemical-resistant gloves should be worn at all times when handling chemicals.

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9. PHYSICAL AND CHEMICAL PROPERTIES

NOTE: The physical and chemical data provided are for the pure components. Descriptive Properties: Nitric acid Cerium nitrate (<20 % of this SRM) (2.3 % of this SRM) Appearance (physical state, color, etc.): colorless to yellow solid liquid Molecular Formula HNO3 Ce(NO3)3 Molar Mass (g/mol) 63.01 326.13 Odor irritating odor not available Odor threshold not available not available pH 1 (1 M) not available Evaporation rate not available not applicable Melting point/freezing point –42 ºC (–43 ºF) not available Relative Density as specific gravity 1.5027 at 25 ºC not available (water = 1) Vapor Pressure 47.9 at 20 ºC not available Vapor Density (air = 1) 3.2 not applicable Viscosity (cP) not available not available Solubility(ies) miscible with water and soluble in water, alcohol, ether and acetone Partition coefficient (n-octanol/water) not available not available Particle Size not applicable not available Thermal Stability Properties Autoignition Temperature not applicable not applicable Thermal Decomposition not applicable not available Initial boiling point and boiling range 83 ºC (181 ºF) not available Explosive Limits, LEL (Volume %) not applicable not applicable Explosive Limits, UEL (Volume %) not applicable not applicable Flash Point not applicable not applicable Flammability (solid, gas) not applicable not applicable

10. STABILITY AND REACTIVITY

Reactivity: Stable at normal temperatures and pressure. Stability: X Stable Unstable Possible Hazardous Reactions: None listed. Conditions to Avoid: Contact with combustible or incompatible materials. Incompatible 材料: Acids, combustible materials, halo carbons, amines, bases, oxidizing materials, metals, halogens, metal salts, metal oxides, reducing agents, peroxides, metal carbide, cyanides. Fire/Explosion Information: See Section 5, “Fire Fighting Measures”. Hazardous Decomposition: Thermal decomposition will form oxides of nitrogen and cerium. Hazardous Polymerization: Will Occur X Will Not Occur

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11. TOXICOLOGICAL INFORMATION

Route of Exposure: X Inhalation X Skin X Ingestion Symptoms Related to the Physical, Chemical and Toxicological Characteristics: Burning pain; severe skin corrosion and eye damage. Potential Health Effects (Acute, Chronic and Delayed): Inhalation: Inhalation of nitric acid can damage the mucous membranes and upper respiratory tract. Short term exposure may cause irritation and inflammation of the upper respiratory tract, coughing, choking, sore throat, shortness of breath, headache, dizziness, and nausea. Long term exposure to acid fumes may cause damage to teeth, bronchial irritation, chronic cough, bronchial pneumonia, and gastrointestinal disturbances. 希土類 salts can cause itching, sensitivity to heat, and lung damage. Skin Contact: Nitric acid can cause severe skin burns. Severity of the damage depends on the concentration and duration of exposure. Effects of acid burns may be delayed. 希土類 salts can cause irritation and hair loss. Eye Contact: Nitric acid can cause severe eye irritation, corneal burns, permanent eye damage, or blindness. Severity of the damage depends on the concentration and duration of exposure. 希土類 salts can cause irritation and eye damage. Ingestion: If ingested, nitric acid can cause severe burns and damage to the gastrointestinal tract. 希土類 salts can cause tearing, diarrhea, bluish skin color, and liver damage. Numerical Measures of Toxicity: Acute Toxicity: Not classified. Nitric acid: Rat, Inhalation LC50: 130 mg/m3 (4 h) Cerium nitrate: Rat, Oral LD50: 3154 mg/kg Skin Corrosion/Irritation: This SRM contains &gt;1 % of nitric acid and it is classified as Category 1B. Serious Eye damage/Eye irritation: This SRM contains &gt;1 % nitric acid and it is classified as Category 1. Respiratory Sensitization: No data available. Skin Sensitization: No data available. Germ Cell Mutagenicity: No data available. Carcinogenicity: Not classified. Listed as a Carcinogen/Potential Carcinogen Yes X No Nitric acid and cerium nitrate are not listed by NTP, IARC or OSHA as carcinogens/potential carcinogens. Reproductive Toxicity: Not classified. Nitric acid: Rat, Oral TDLo: 21 150 mg/kg (pregnant 1 d to 21 d) Nitric acid: Rat, Oral TDLo: 2345 mg/kg (pregnant 18 d) Cerium nitrate: Rat, Intratesticular TDLo: 26 092 µg/kg (1 d) Specific Target Organ Toxicity, Single Exposure: No data available. Specific Target Organ Toxicity, Repeated Exposure: No data available. Aspiration Hazard: No data available.

12. ECOLOGICAL INFORMATION

Ecotoxicity Data Nitric acid: Fish, mosquitofish (Gambusia affinis) LC50: 72 mg/L (96 h) Cerium nitrate: Invertebrate, water flea, (Daphnia magna) EC50: >100 mg/L (48 h) Persistence and Degradability: No data available. Bioaccumulative Potential: No data available. Mobility in Soil: No data available. Other Adverse effects: No data available.

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13. DISPOSAL CONSIDERATIONS

Waste Disposal: Dispose of waste in accordance with all applicable federal, state, and local regulations. Nitric acid subject to disposal regulations: U.S. EPA 40 CFR 262, Hazardous Waste Numbers: D001, D002. No data available for cerium nitrate.

14. TRANSPORTATION INFORMATION

U.S. DOT and IATA: UN1760, Corrosive liquid, n.o.s. (contains nitric acid), Hazard Class 8, Packing Group II.

15. REGULATORY INFORMATION

U.S. Regulations: CERCLA Sections 102a/103 (40 CFR 302.4): Nitric acid, 1000 lbs. (454 kg) final RQ SARA Title III Section 302 (40 CFR 355.30): Nitric acid, 1000 lbs. (454 kg) TPQ SARA Title III Section 304 (40 CFR 355.40): Nitric acid, 1000 lbs. (454 kg) EPCRA RQ SARA Title III Section 313 (40 CFR 372.65): 1 % de minimis concentration for nitric acid OSHA Process Safety (29 CFR 1910.119): Regulated for nitric acid at higher concentrations 500 lbs. TQ (≥94.5 % by weight). SARA Title III Sections 311/312 Hazardous Categories (40 CFR 370.21): ACUTE HEALTH: Yes CHRONIC HEALTH: Yes FIRE: No REACTIVE: No PRESSURE: No State Regulations: Not listed under California Proposition 65. U.S. TSCA Inventory: Nitric acid and cerium nitrate are listed. TSCA 12(b), Export Notification: Not listed. Canadian Regulations: WHMIS Information is not provided for this material.

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16. OTHER INFORMATION

Issue Date: 2016年12月8日 情報源s: ChemADVISOR, Inc., SDS Nitric Acid, 2015年12月9日. ChemADVISOR, Inc., SDS Cerous Nitrate, 2015年12月9日. Hazardous Substances Data Bank (HSDB), National Library of Medicine&#39;s TOXNET system, Nitric Acid CAS No. 7697-37-2; available at http://toxnet.nlm.nih.gov (accessed Dec 2016).

Key of Acronyms: ACGIH American Conference of Governmental Industrial NRC Nuclear Regulatory Commission Hygienists ALI Annual Limit on Intake NTP National Toxicology Program CAS Chemical Abstracts Service OSHA Occupational Safety and Health Administration CERCLA Comprehensive Environmental Response, PEL Permissible Exposure Limit Compensation, and Liability Act CFR Code of Federal Regulations RCRA Resource Conservation and Recovery Act DOT Department of Transportation REL おすすめ Exposure Limit EC50 Effective Concentration, 50 % RM Reference Material EINECS European Inventory of Existing Commercial RQ Reportable Quantity Chemical Substances EPCRA Emergency Planning and Community Right-to-Know RTECS Registry of Toxic Effects of Chemical Substances Act IARC International Agency for Research on Cancer SARA Superfund Amendments and Reauthorization Act IATA International Air Transport Association SCBA Self-Contained Breathing Apparatus IDLH Immediately Dangerous to Life and Health SRM Standard Reference Material LC50 Lethal Concentration, 50 % STEL Short Term Exposure Limit LD50 Lethal Dose, 50 % STOT Specific Target Organ Toxicity LEL Lower Explosive Limit TLm Threshold Limit, median SDS 安全データシート TLV Threshold Limit Value NFPA National Fire Protection Association TPQ Threshold Planning Quantity NIOSH National Institute for Occupational Safety and Health TSCA Toxic Substances Control Act NIST 米国国立標準技術研究所 TWA Time Weighted Average n.o.s. Not Otherwise Specified UEL Upper Explosive Limit WHMIS Workplace Hazardous 材料 Information System

Disclaimer: Physical and chemical data contained in this SDS are provided only for use in assessing the hazardous nature of the material. The SDS was prepared carefully, using current references; however, NIST does not certify the data in the SDS. The certified values for this material are given in the NIST Certificate of Analysis. Users of this SRM should ensure that the SDS in their possession is current. This can be accomplished by contacting the SRM Program: telephone (301) 975-2200; fax (301) 948-3730; e-mail srmmsds@nist.gov; or via the Internet at http://www.nist.gov/srm.

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