Cerium(IV) oxide, REacton® ALFAA11327 SDS

Page 1 / 7 SAFETY DATA SHEET Creation Date 09-Jan-2012 Revision Date 23-Jul-2026 Version 5

ALFAA11327

Cerium(IV) oxide, REacton®

SECTION 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

产品说明:产品说明:产品说明:产品说明: 二氧化铈二氧化铈二氧化铈二氧化铈 Product Description: Cerium(IV) oxide, REacton®

Cat No. : 11327 Synonyms Cerium dioxide CAS No 1306-38-3 Molecular Formula Ce O2

Supplier Avocado Research Chemicals Ltd. (Part of Thermo Fisher Scientific) Shore Road, Heysham Lancashire, LA3 2XY, United Kingdom Office Tel: +44 (0) 1524 850506 Office Fax: +44 (0) 1524 850608

Emergency Telephone Number For information US call: 001-800-227-6701 / Europe call: +32 14 57 52 11 Emergency Number US:001-201-796-7100 / Europe: +32 14 57 52 99 CHEMTREC Tel. No. US:001-800-424-9300 / Europe:001-703-527-3887

E-mail address begel.sdsdesk@thermofisher.com

Recommended Use Laboratory chemicals. Uses advised against No Information available

SECTION 2. HAZARD IDENTIFICATION

Physical State Appearance Odor Powder Solid Light yellow Odorless

Emergency Overview The product contains no substances which at their given concentration are considered to be hazardous to health.

Classification of the substance or mixture Based on available data, the classification criteria are not met

Label Elements

None required

Physical and Chemical Hazards None identified. Health Hazards The product contains no substances which at their given concentration are considered to be hazardous to health. Environmental hazards Contains no substances known to be hazardous to the environment or not degradable in waste water treatment plants. Is not likely mobile in the environment due its low water solubility. Spillage unlikely to penetrate soil.

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ALFAA11327 SAFETY DATA SHEET Revision Date 23-Jul-2026Page 2 / 7 Cerium(IV) oxide, REacton® ______________________________________________________________________________________________

Other Hazards

This product does not contain any known or suspected endocrine disruptors.

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

Component CAS No Weight % Cerium oxide 1306-38-3 >95

SECTION 4. FIRST AID MEASURES

Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Skin Contact Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.

Inhalation Remove from exposure, lie down. Remove to fresh air.

Ingestion Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Drink plenty of water. If possible drink milk afterwards.

Most important symptoms and effects No information available.

Self-Protection of the First Aider No special precautions required.

Notes to Physician Treat symptomatically.

SECTION 5. FIRE-FIGHTING MEASURES

Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Extinguishing media which must not be used for safety reasons No information available.

Specific Hazards Arising from the Chemical Thermal decomposition can lead to release of irritating gases and vapors.

Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.

SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal Precautions Ensure adequate ventilation.

Environmental Precautions See Section 12 for additional Ecological Information. ______________________________________________________________________________________________ Page 2

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Methods for Containment and Clean Up Sweep up and shovel into suitable containers for disposal.

Refer to protective measures listed in Sections 8 and 13.

SECTION 7. HANDLING AND STORAGE

Handling Avoid contact with skin and eyes. Avoid contact with skin and clothing. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Avoid breathing vapors or mists. Do not ingest. If swallowed then seek immediate medical assistance. Wash thoroughly after handling.

Storage Keep in a dry, cool and well-ventilated place. Keep container tightly closed.

Specific Use(s) Use in laboratories

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Control Parameters

Monitoring methods BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. MDHS14/3 General methods for sampling and gravimetric analysis of respirable and inhalable dust

Exposure Controls

Engineering Measures None under normal use conditions. .

Personal protective equipment

Eye Protection Wear safety glasses with side shields (or goggles) (European standard - EN 166)

Hand Protection Protective gloves

Glove material Breakthrough time Glove thickness EU standard Glove comments Natural rubber See manufacturers - EN 374 (minimum requirement) Nitrile rubber recommendations Neoprene PVC Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Remove gloves with care avoiding skin contamination.

Skin and body protection Long sleeved clothing

Respiratory Protection No protective equipment is needed under normal use conditions.

Large scale/emergency use Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits

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ALFAA11327 SAFETY DATA SHEET Revision Date 23-Jul-2026Page 4 / 7 Cerium(IV) oxide, REacton® ______________________________________________________________________________________________ are exceeded or if irritation or other symptoms are experienced Recommended Filter type: Particle filter

Small scale/Laboratory use Maintain adequate ventilation

Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.

Environmental exposure controls No information available.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance Light yellow Physical State Powder Solid

Odor Odorless Odor Threshold No data available pH No information available Melting Point/Range 2600 °C / 4712 °F Softening Point No data available Boiling Point/Range No information available Flash Point No information available Method - No information available Evaporation Rate Not applicable Solid Flammability (solid,gas) No information available Explosion Limits No data available

Vapor Pressure No information available Vapor Density Not applicable Solid Specific Gravity / Density 7.130 Bulk Density No data available Water Solubility Insoluble Solubility in other solvents No information available Partition Coefficient (n-octanol/water) Autoignition Temperature No data available Decomposition Temperature No data available Viscosity Not applicable Solid Explosive Properties No information available Oxidizing Properties No information available

Molecular Formula Ce O2 Molecular Weight 172.12

SECTION 10. STABILITY AND REACTIVITY

Stability Stable under normal conditions.

Hazardous Reactions No information available. Hazardous Polymerization No information available.

Conditions to Avoid Incompatible products.

Materials to avoid Strong oxidizing agents. Oxidizing agent.

Hazardous Decomposition Products Thermal decomposition can lead to release of irritating gases and vapors.

SECTION 11. TOXICOLOGICAL INFORMATION

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(a) acute toxicity; Component LD50 Oral LD50 Dermal LC50 Inhalation Cerium oxide >5000 mg/kg ( Rat ) >2000 mg/kg ( Rat ) >5.05 mg/L ( Rat ) 4 h

(b) skin corrosion/irritation; Based on available data, the classification criteria are not met

(c) serious eye damage/irritation; Based on available data, the classification criteria are not met

(d) respiratory or skin sensitization; Respiratory Based on available data, the classification criteria are not met Skin Based on available data, the classification criteria are not met

(e) germ cell mutagenicity; Based on available data, the classification criteria are not met

Not mutagenic in AMES Test

(f) carcinogenicity; Based on available data, the classification criteria are not met

There are no known carcinogenic chemicals in this product

(g) reproductive toxicity; Based on available data, the classification criteria are not met

(h) STOT-single exposure; Based on available data, the classification criteria are not met

(i) STOT-repeated exposure; Based on available data, the classification criteria are not met

Target Organs None known.

(j) aspiration hazard; Not applicable Solid

Other Adverse Effects The toxicological properties have not been fully investigated.

Symptoms / effects,both acute and No information available delayed

SECTION 12. ECOLOGICAL INFORMATION

Ecotoxicity effects Do not empty into drains. .

Component Freshwater Fish Water Flea Freshwater Algae Microtox Cerium oxide LC50 >100 mg/L/96h EC50 >100 mg/L/48h (Brachydanio rerio)

Persistence and Degradability Persistence Insoluble in water. Degradability Not relevant for inorganic substances.

Bioaccumulative Potential May have some potential to bioaccumulate

Mobility in soil Spillage unlikely to penetrate soil Is not likely mobile in the environment due its low water ______________________________________________________________________________________________ Page 5

ALFAA11327 SAFETY DATA SHEET Revision Date 23-Jul-2026Page 6 / 7 Cerium(IV) oxide, REacton® ______________________________________________________________________________________________ solubility

Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors Persistent Organic Pollutant This product does not contain any known or suspected substance Ozone Depletion Potential This product does not contain any known or suspected substance

SECTION 13. DISPOSAL CONSIDERATIONS

Waste from Residues/Unused Chemical waste generators must determine whether a discarded chemical is classified as a Products hazardous waste. Consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.

Contaminated Packaging Empty remaining contents. Dispose of in accordance with local regulations. Do not re-use empty containers.

Other Information Waste codes should be assigned by the user based on the application for which the product was used.

SECTION 14. TRANSPORT INFORMATION

Road and Rail Transport Not Regulated

IMDG/IMO Not regulated

IATA Not regulated

Special Precautions for User No special precautions required

SECTION 15. REGULATORY INFORMATION

International Inventories X = listed, China (IECSC), Europe (EINECS/ELINCS/NLP), U.S.A. (TSCA), Canada (DSL/NDSL), Philippines (PICCS), Japan (ENCS), Japan (ISHL), Australia (AICS), Korea (KECL).

Component The List of IECSC EINECS TSCA DSL PICCS ENCS ISHL AICS KECL Inventory of dangerous Hazardous goods GB Chemicals 12268 - (2015 2012 Edition) Cerium oxide - - X 215-150-4 X X X X X X KE-05392

National Regulations

SECTION 16. OTHER INFORMATION

Prepared By Health, Safety and Environmental Department Creation Date 09-Jan-2012 Revision Date 23-Jul-2026 Revision Summary Not applicable.

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ALFAA11327 SAFETY DATA SHEET Revision Date 23-Jul-2026Page 7 / 7 Cerium(IV) oxide, REacton® ______________________________________________________________________________________________ Training Advice Chemical hazard awareness training, incorporating labelling, Safety Data Sheets (SDS), Personal Protective Equipment (PPE) and hygiene.

Legend

CAS - Chemical Abstracts Service TSCA - United States Toxic Substances Control Act Section 8(b) Inventory EINECS/ELINCS - European Inventory of Existing Commercial Chemical DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances/EU List of Notified Chemical Substances Substances List PICCS - Philippines Inventory of Chemicals and Chemical Substances ENCS - Japanese Existing and New Chemical Substances IECSC - Chinese Inventory of Existing Chemical Substances AICS - Australian Inventory of Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances NZIoC - New Zealand Inventory of Chemicals

WEL - Workplace Exposure Limit TWA - Time Weighted Average ACGIH - American Conference of Governmental Industrial Hygienists IARC - International Agency for Research on Cancer DNEL - Derived No Effect Level PNEC - Predicted No Effect Concentration RPE - Respiratory Protective Equipment LD50 - Lethal Dose 50% LC50 - Lethal Concentration 50% EC50 - Effective Concentration 50% NOEC - No Observed Effect Concentration POW - Partition coefficient Octanol:Water PBT - Persistent, Bioaccumulative, Toxic vPvB - very Persistent, very Bioaccumulative

ICAO/IATA - International Civil Aviation Organization/International Air IMO/IMDG - International Maritime Organization/International Maritime Transport Association Dangerous Goods Code ADR - European Agreement Concerning the International Carriage of MARPOL - International Convention for the Prevention of Pollution from Dangerous Goods by Road Ships OECD - Organisation for Economic Co-operation and Development ATE - Acute Toxicity Estimate BCF - Bioconcentration factor VOC - (Volatile Organic Compound)

Key literature references and sources for data https://echa.europa.eu/information-on-chemicals Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS

Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text

End of Safety Data Sheet

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