Copper Isotope SDS — Copper, Enriched Copper

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 1/9

Section 1: Identification of the Substance/Mixture and of the Company/Undertaking

Product Identifier: Identification as on the label/Trade name: Copper, Enriched Copper. Molecular weight: 63.546 Chemical formula: Cu Synonyms: Enriched Copper. Details of the supplier of the Safety Data Sheet: Neonest AB Storgatan 70C, Solna SE-17152 Sweden Contact details: +46-76-219-9731 24-hour Emergency Contact: Swedish Poisons Centre Phone: 112 - Ask for Poisons Information, 112 – begär Giftinformation . Other International Contacts: CHEMTREC 24-hour: +1-703-741-5500 (US + Worldwide) NHS: 111 (UK) Charite: +49 30 450 531 000 (Netherlands) INTCF: +34 917689800 (Spain) CapTv: +33 1 40 05 48 48 (France)

Section 2: Hazards Identification

Classification of the substances or mixture: The mixture is classified according to: Regulation EC 1272/2008 [EU-GHS/CLP] Hazard classes/Hazard categories: Hazard statement: Not classified as hazardous. None required. Label elements: Hazard pictograms: Not required. Signal Words: Not required. Hazard Statements: Not required. Precautionary Statements: None. Other hazards: None known.

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 2/9

Section 3: Composition/Information on Ingredients

Substance/Mixture: Substance. Ingredients: Substance name (IUPAC/EC) CAS - No. Molecular weight Concentration % by weight Classification EC1272/2008 EC - No. Copper 7440-50-8 63.546 >99% Not Classified. 231-159-6 For explanation of abbreviations see Section 16.

Section 4: First - Aid Measures

Description of first aid measures: In case of inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. In case of skin contact: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention if irritation develops or persists. In case of eye contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. In case of ingestion: Induce vomiting. If victim is conscious and alert, give 2-4 cups of milk or water. Get medical attention. Most important symptoms and effects, both acute and delayed: Inhalation: Dust is irritating to the respiratory tract. Inhalation of fumes may cause metal fume fever, which is characterized by flu-like symptoms with metallic taste, fever, chills, cough, weakness, chest pain, muscle pain and increased white blood cell count. Eyes: Causes eye irritation. Skin contact: Causes skin irritation. May cause skin discoloration. Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhoea. May cause liver and kidney damage. Indication of any immediate medical attention and special treatment needed: Treat symptomatically. Show this safety data sheet to a physician or emergency room.

Section 5: Fire - Fighting Measures

Extinguisher media: Suitable extinguisher media: Use any means suitable for extinguishing surrounding fire. Unsuitable extinguishing media: None known. Special hazards arising from the mixture: None known. Advice for fire-fighters: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Further information: Standard procedure for chemical fires. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 3/9

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Personal precautions: Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Use proper personal protective equipment as indicated in Section 8. Environmental precautions: Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. Local authorities should be advised if significant spillages cannot be contained. Methods for containment and cleaning up: Methods for cleaning up: Sweep up, then place into a suitable container for disposal. Avoid generating dust. Reference to other sections: Treat recovered material as described in the section "Disposal considerations".

Section 7: Handling and Storage

Precautions for safe handling: Advice on safe handling: Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Hygiene measures: Do not eat, drink or smoke when using this product. Conditions for safe storage, including incompatibilities: Requirements for storage areas and containers: Store in a tightly closed container. Store in a cool, dry, well- ventilated area away from incompatible substances. Do not expose to air.

Section 8: Exposure Controls/ Personal Protection

Control parameters: Occupational exposure limits: ACGIH: 0.2 mg/m 3 TWA (fume); 1 mg/m 3 TWA (dusts and mists). NIOSH: as Cu: 1 mg/m 3 TWA (dusts and mists); 0.1 mg/m 3 TWA (fume) dusts as mists as Cu: 100 mg/m 3 IDLH. OSHA: Final PELs: 0.1 mg/m 3 TWA (fume); 1 mg/m 3 TWA (dusts and mists). OSHA: Vacated PELs: 0.1 mg/m 3 TWA (fume, dusts, mists as Cu). Exposure controls: Appropriate engineering controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Individual protection measures, such as personal protective equipment: Eye/face protection: Use safety glasses. If there is a potential for exposure to particles which could cause eye discomfort, wear chemical goggles. Maintain eye wash fountain and quick-drench facilities in work area. Hand protection: Use chemical resistant gloves. Examples of preferred glove barrier materials include: Butyl rubber, Neoprene, Nitrile/butadiene rubber, Polyethylene, Ethyl vinyl alcohol laminate, polyvinyl alcohol, Polyvinyl chloride. Body protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 4/9 Respiratory protection: If discomfort is experienced, use an approved air-purifying respirator. Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines.

Section 9: Physical and Chemical Properties

Information on basic physical and chemical properties Appearance (form): Solid. Colour: Red to brown. Odour: No data available. Odour threshold: No data available. Molecular Weight: 63.546 pH (concentration): No data available. Melting point/range (° C): 1083 °C Boiling point/range (° C): 2595 °C Freezing point (°C): No data available. Flash point (° C): No data available. Evaporation rate: No data available. Flammability (solid, gas): No data available. Ignition temperature (° C): No data available. Upper/lower flammability/explosive limits: No data available. Vapour pressure (20 ° C): 1mm Hg @1628 °C Vapour density: No data available. Relative densi ty (25 ° C): 8.92 Water solubility (g/L ) at 20 ° C: Negligible (< 0.1%). n-Octanol/Water partition coefficient : No data available. Auto-ignition temperature: No data available. Decomposition temperature: No data available. Viscosity, dynamic (mPa s): No data available. Explosive properties: The substance or mixture is not classified as explosive. Oxidising properties: The substance or mixture is not classified as oxidizing.

Section 10: Stability and Reactivity

Reactivity: No dangerous reaction known under conditions of normal use. Chemical stability: Stable under normal conditions. Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use. Conditions to avoid: D ust generation, moisture, exposure to air . Incompatible materials: Ammonium nitrate, bromates, iodates, chlorates, ethylene oxide, hydrazoic acid, potassium oxide, dimethyl sulphoxide + trichloroacetic acid, hydrogen peroxide, sodium peroxide, sodium azide, sulphuric acid, hydrogen sulphide + air, and lead azide. Ignites on contact with chlorine, fluorine (above 121 ºC), chlorine trifluoride, and hydrazinium nitrate (above 70 ºC). Incompatible with 1 -bromo-2-propyne, potassium dioxide, and actylenic compounds. Hazardous decomposition products: Copper fumes.

Section 11: Toxicological Information

Information on toxicological effects:

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 5/9 Not classified based on available information. Classification according to GHS (1272/2008/EG, CLP) Skin corrosion/irritation: Not classified based on available information. Serious eye damage/eye irritation: Not classified based on available information. Respiratory or skin sensitisation: Not classified based on available information. Germ cell mutagenicity: Not classified based on available information. Carcinogenicity: Not classified based on available information. Reproductive toxicity: Not classified based on available information. Specific target organ toxicity – single exposure (STOT): Not classified based on available information. Specific target organ toxicity (STOT) – repeated exposure: Not classified based on available information. Aspiration toxicity: Not classified based on available information.

Section 12: Ecological Information

Toxicity: Toxicity to Fish: Mortality LOEC, Oncorhynchus mykiss , 0.022 mg/l, 96 hours. Toxicity to Daphnia and Other Aquatic Invertebrates: Mortality NOEC, Daphnia, 0.004 mg/l, 24 hours. EC50 - Daphnia magna, 0.04 - 0.05 mg/l, 48 hours. Persistence and degradability: No data available. Bioaccumulative potential: Cyprinus carpio , 40 days, 200 mg/l. Bioconcentration factor (BCF): 108. Mobility in soil: No data available. Results of PBT& vPvB assessment: Not relevant. Other adverse effects: An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Very toxic to aquatic life with long-lasting effects. Avoid release to the environment.

Section 13: Disposal Considerations

Waste treatment methods: Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.

Section 14: Transport Information

UN number: Not regulated as a dangerous good. UN proper shipping name: Not regulated as a dangerous good. Transport hazard class(es): Not regulated as a dangerous good. Packing group: Not regulated as a dangerous good. Environmental hazards: Not regulated as a dangerous good.

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 6/9 Special precautions for user: Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR. Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable.

Section 15: Regulatory Information

EU regulations: Regulation (EC) No. 1005/2009 on substances that deplete the ozone layer, Annex I and II, as amended Not listed. Regulation (EC) No. 850/2004 on persistent organic pollutants, Annex I Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 1 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 2 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 3 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex V as amended Not listed. Regulation (EC) No. 166/2006 Annex II Pollutant Release and Transfer Registry Not listed. Regulation (EC) No. 1907/2006, REACH Article 59(10) Candidate List as currently published by ECHA Not listed. Authorisations: Regulation (EC) No. 1907/2006, REACH Annex XIV Substances subject to authorization, as amended Not listed. Restrictions on use: Regulation (EC) No. 1907/2006 Annex XVII Substances subject to restriction on marketing and use Not regulated. Regulation (EC) No. 1907/2006, REACH Annex XVII Substances subject to restriction on marketing and use as amended Not listed. Directive 2004/37/EC on the protection of workers from the risks related to exposure to carcinogens and mutagens at work Not regulated. Directive 92/85/EEC: on the safety and health of pregnant workers and workers who have recently given birth or are breastfeeding. Not regulated. Other EU regulations: Directive 2012/18/EU on major accident hazards involving dangerous substances Not listed. Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work.

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 7/9 Always applicable. Directive 94/33/EC on the protection of young people at work Not listed. Other regulations: The product is classified and labelled in accordance with EC directives or respective national laws. This Safety Data Sheet complies with the requirements of Regulation (EC) No 1907/2006, as amended. SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III,

Section 302.

SARA 313 Components: The following components are subject to reporting levels established by SARA Title III, Section 313: Copper, CAS No. 7440-50-8, Revision Date: 2007-07-01. SARA 311/312 Hazards: Fire Hazard, Chronic Health Hazard. Massachusetts Right to Know Components: Copper, CAS No.7440-50-8, Revision Date 2007-07-01 Pennsylvania Right to Know Components: Copper, CAS No.7440-50-8, Revision Date 2007-07-01 New Jersey Right to Know Components: Copper, CAS No.7440-50-8, Revision Date 2007-07-01 California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects or any other reproductive harm. National regulations: Follow national regulation for work with chemical agents. Chemical safety assessment: No Chemical Safety Assessment has been carried out.

Section 16: Other Information

List of abbreviations: ACGIH American Conference of Governmental Industrial Hygienists ADR European Agreement Concerning the International Carriage of Dangerous Goods by Road ALARA As Low As Is Reasonably Achievable AMU Atomic Mass Unit ANSI American National Standards Institute BLS Basic Life Support CAM Continuous Air Monitor CAS Chemical Abstracts Service (division of the American Chemical Society) CEN European Committee for Standardization CERCLA Comprehensive Environmental Response Compensation and Liability Act CLP Classification, Labelling and Packaging (European Union) CPR Controlled Products Regulations (Canada) CWA Clean Water Act (USA) DAC Derived Air Concentration (USA) DOE United States Department of Energy (USA) DOT United States Department of Transportation (USA) DSL Domestic Substances List (Canada) EC50 Half Maximal Effective Concentration EINECS European Inventory of Existing Commercial Chemical Substances EHS Environmentally Hazardous Substance ELINCS European List of Notified Chemical Substances EMS Emergency Response Procedures for Ships Carrying Dangerous Goods EPA Environmental Protection Agency (USA) EPCRA Emergency Planning and Community Right-To-Know Act (EPCRA) of 1986 GHS Globally Harmonized System HMIS Hazardous Materials Identification System (USA)

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 8/9 IARC International Agency for Research on Cancer IATA International Air Transport Association IBC Intermediate Bulk Containers ICAO International Civil Aviation Organization IDLH Immediately Dangerous to Life or Health IMDG International Maritime Code for Dangerous Goods LC50 Lethal concentration, 50 percent LD50 Lethal dose, 50 percent LDLO Lethal Dose Low LOEC Lowest-Observed-Effective Concentration MARPOL International Convention for the Prevention of Pollution from Ships MSHA Mine Safety and Health Administration (USA) NCRP National Council on Radiation Protection & Measurements (USA) NDSL Non-Domestic Substances List (Canada) NFPA National Fire Protection Association (USA) NIOSH National Institute for Occupational Safety and Health (USA) NOEC No Observed Effect Concentration N.O.S. Not Otherwise Specified NRC Nuclear Regulatory Commission (USA) NTP National Toxicology Program (USA) OSHA Occupational Safety and Health Administration (USA) PBT Persistent Bioaccumulative and Toxic Chemical PEL Permissible Exposure Limit PIH Poisonous by Inhalation Hazard RCRA Resource Conservation and Recovery Act (USA) RCT Radiation Control Technician REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (Europe) RID Regulations Concerning the International Transport of Dangerous Goods by Rail RTECS Registry of Toxic Effects of Chemical Substances SARA Superfund Amendments and Reauthorization Act (USA) TDG Transportation of Dangerous Goods (Canada) TIH Toxic by Inhalation Hazard TLV Threshold Limit Value TPQ Threshold Planning Quantity TSCA Toxic Substances Control Act TWA Time Weighted Average UN United Nations (Number) VOC Volatile Organic Compound vPvB Very Persistent Very Bioaccumulative Chemical WGK Wassergefährdungsklassen (Germany: Water Hazard Classes) WHMIS Workplace Hazardous Materials Information System References: Not available. Full text of any H-statements not written out in full under Sections 2 to 15: None. Revision information: None. Training information:

Safety Data Sheet for Copper, Enriched Copper According to ISO 11014:2010 First Print Date: 5-Mar-2015 Revision Date: 12-Aug-2019 Version: 1.1.1. Safety Data Sheet (SDS) for Copper, Enriched Copper https://www.buyisotope.com Page 9/9 Follow training instructions when handling this material. Further Information: The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.