Gadolinium oxide - enriched gadolinium isotopes SDS

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Section 1: Identification of the Substance/Mixture and of the Company/Undertaking

Product Identifier:

Identification as on the label/Trade name: Gadolinium Oxide, Enriched Gadolinium. Molecular weight: 362.50 Chemical formula: Gd2O3 Synonyms: None.

Details of the supplier of the Safety Data Sheet:

Neonest AB Storgatan 70C, Solna SE-17152 Sweden

Contact details:

+46-76-219-9731

24-hour Emergency Contact:

Swedish Poisons Centre Phone: 112 - Ask for Poisons Information, 112 – begär Giftinformation.

Other International Contacts: CHEMTREC 24-hour: +1-703-741-5500 (US + Worldwide) NHS: 111 (UK) Charite: +49 30 450 531 000 (Netherlands) INTCF: +34 917689800 (Spain) CapTv: +33 1 40 05 48 48 (France)

Section 2: Hazards Identification

Classification of the substances or mixture: The mixture is classified according to: Regulation EC 1272/2008 [EU-GHS/CLP]

Hazard classes/Hazard categories: Hazard statement: Not classified as hazardous. None required.

Label elements:

Hazard pictograms: Not required. Signal Words: Not required. Hazard Statements: Not required. Precautionary Statements: None. Other hazards: None known.

Safety Data Sheet (SDS) for Gadolinium Oxide, Enriched Gadolinium https://www.buyisotope.com Page 1/8

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Section 3: Composition/Information on Ingredients

Substance/Mixture: Substance. Ingredients:

CAS-No. Molecular Concentration Classification Substance name (IUPAC/EC) EC-No. weight % by weight EC1272/2008

12064-62-9 Digadolinium trioxide 362.50 >99% Not Classified. 235-060-9

For explanation of abbreviations see Section 16.

Section 4: First-Aid Measures

Description of first aid measures:

In case of inhalation: Move patient to fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact: Remove contaminated clothing, then flush with water for at least 15 minutes. Wash clothing thoroughly before reuse. Consult a physician. In case of eye contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention. In case of ingestion: Do not induce vomiting. Get immediate medical help. If patient is conscious, give large quantity of water/milk. If irritation continues, seek medical attention immediately.

Most important symptoms and effects, both acute and delayed: Eyes: Causes serious eye irritation. Indication of any immediate medical attention and special treatment needed: Treat symptomatically. Show this safety data sheet to a physician or emergency room.

Section 5: Fire-Fighting Measures

Extinguisher media:

Suitable extinguisher media: Use firefighting measures that are appropriate to the surrounding fire. Unsuitable extinguishing media: None known. Special hazards arising from the mixture: None known. Advice for fire-fighters: Wear self-contained breathing apparatus and protective clothing. Further information: Standard procedure for chemical fires. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures:

Personal precautions: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. For personal protection, see section 8. Environmental precautions: Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. Local authorities should be advised if significant spillages cannot be contained.

Safety Data Sheet (SDS) for Gadolinium Oxide, Enriched Gadolinium https://www.buyisotope.com Page 2/8

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Methods for containment and cleaning up: Methods for cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable closed containers for disposal.

Reference to other sections: Treat recovered material as described in the section "Disposal considerations".

Section 7: Handling and Storage

Precautions for safe handling:

Advice on safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Hygiene measures: Do not eat, drink or smoke when using this product.

Conditions for safe storage, including incompatibilities: Requirements for storage areas and containers: Keep tightly sealed when not in use. Store in a cool, dry area. Hygroscopic. Store under inert gas.

Section 8: Exposure Controls/Personal Protection

Control parameters:

Occupational exposure limits: Contains no substances with occupational exposure limit values.

Exposure controls:

Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Individual protection measures, such as personal protective equipment:

Eye/face protection: Use safety glasses. If there is a potential for exposure to particles which could cause eye discomfort, wear ANSI-approved chemical goggles. Maintain eye wash fountain and quick-drench facilities in work area. Hand protection: Use chemical resistant gloves. Examples of preferred glove barrier materials include: Butyl rubber, Neoprene, Nitrile/butadiene rubber, Polyethylene, Ethyl vinyl alcohol laminate, polyvinyl alcohol, Polyvinyl chloride. Body protection: Wear protective clothing as appropriate. Respiratory protection: If discomfort is experienced, use an approved air-purifying respirator. Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines.

Section 9: Physical and Chemical Properties

Information on basic physical and chemical properties

Appearance (form): Solid (hygroscopic powder). Colour: White. Odour: Odourless. Odour threshold: No data available. Molecular Weight: 362.50 pH (concentration): No data available.

Safety Data Sheet (SDS) for Gadolinium Oxide, Enriched Gadolinium https://www.buyisotope.com Page 3/8

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Melting point/range (°C): 2420 °C Boiling point/range (°C): No data available. Freezing point (°C): No data available. Flash point (°C): No data available. Evaporation rate: No data available. Flammability (solid, gas): No data available. Ignition temperature (°C): No data available. Upper/lower flammability/explosive limits: No data available. Vapour pressure (20 °C): No data available. Vapour density: No data available. Relative density (25 °C): 7.407 g/cm3 Water solubility (g/L) at 20 °C: Very slightly soluble in water. n-Octanol/Water partition coefficient: No data available. Auto-ignition temperature: No data available. Decomposition temperature: No data available. Viscosity, dynamic (mPa s): No data available. Explosive properties: The substance or mixture is not classified as explosive. Oxidising properties: The substance or mixture is not classified as oxidizing.

Section 10: Stability and Reactivity

Reactivity: No dangerous reaction known under conditions of normal use. Chemical stability: Stable under normal conditions. Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use. Conditions to avoid: Heat. Incompatible materials: Air, halogens, and strong acids. Hazardous decomposition products: Toxic fumes.

Section 11: Toxicological Information

Information on toxicological effects:

Acute Toxicity: LD50 Oral Rat: > 5000 mg/kg.

Classification according to GHS (1272/2008/EG, CLP)

Skin corrosion/irritation: Not classified based on available information. Serious eye damage/eye irritation: Not classified based on available information. Respiratory or skin sensitisation: Not classified based on available information. Germ cell mutagenicity: Not classified based on available information. Carcinogenicity: NTP: No IARC: No OSHA: No Reproductive toxicity:

Safety Data Sheet (SDS) for Gadolinium Oxide, Enriched Gadolinium https://www.buyisotope.com Page 4/8

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Not classified based on available information. Specific target organ toxicity – single exposure (STOT): Not classified based on available information. Specific target organ toxicity (STOT) – repeated exposure: Not classified based on available information. Aspiration toxicity: Not classified based on available information.

Section 12: Ecological Information

Toxicity: No data available. Persistence and degradability: No data available. Bioaccumulative potential: No data available. Mobility in soil: No data available. Results of PBT& vPvB assessment: Not relevant. Other adverse effects: Do not allow material to be released to the environment.

Section 13: Disposal Considerations

Waste treatment methods: Contact local hazardous or chemical waste disposal agency for regulations. Dispose of in accordance with local and national regulations.

Section 14: Transport Information

UN number: Not regulated as a dangerous good. UN proper shipping name: Not regulated as a dangerous good. Transport hazard class(es): Not regulated as a dangerous good. Packing group: Not regulated as a dangerous good. Environmental hazards: Not regulated as a dangerous good. Special precautions for user: Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR. Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable.

Section 15: Regulatory Information

EU regulations:

Regulation (EC) No. 1005/2009 on substances that deplete the ozone layer, Annex I and II, as amended Not listed. Regulation (EC) No. 850/2004 on persistent organic pollutants, Annex I Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 1 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 2 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 3 as amended

Safety Data Sheet (SDS) for Gadolinium Oxide, Enriched Gadolinium https://www.buyisotope.com Page 5/8

Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex V as amended Not listed. Regulation (EC) No. 166/2006 Annex II Pollutant Release and Transfer Registry Not listed. Regulation (EC) No. 1907/2006, REACH Article 59(10) Candidate List as currently published by ECHA Not listed.

Authorisations: Regulation (EC) No. 1907/2006, REACH Annex XIV Substances subject to authorization, as amended Not listed.

Restrictions on use: Regulation (EC) No. 1907/2006 Annex XVII Substances subject to restriction on marketing and use Not regulated. Regulation (EC) No. 1907/2006, REACH Annex XVII Substances subject to restriction on marketing and use as amended Not listed. Directive 2004/37/EC on the protection of workers from the risks related to exposure to carcinogens and mutagens at work Not regulated. Directive 92/85/EEC: on the safety and health of pregnant workers and workers who have recently given birth or are breastfeeding. Not regulated.

Other EU regulations: Directive 2012/18/EU on major accident hazards involving dangerous substances Not listed. Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Always applicable. Directive 94/33/EC on the protection of young people at work Not listed.

Other regulations: The product is classified and labelled in accordance with EC directives or respective national laws. This Safety Data Sheet complies with the requirements of Regulation (EC) No 1907/2006, as amended. SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III,

Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312: Hazards Acute Health Hazard. Massachusetts Right to Know Components: No components are subject to the Massachusetts Right to Know Act. Pennsylvania Right to Know Components: Digadolinium trioxide / CAS No. 12064-62-9 New Jersey Right to Know Components: Digadolinium trioxide / CAS No. 12064-62-9 California Prop. 65 Components This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm. TSCA Listed: All components are listed.

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Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

Regulation (EC) No. 1272/2008: N/A Canada WHMIS Classification: N/A National regulations: Follow national regulation for work with chemical agents. Chemical safety assessment: No Chemical Safety Assessment has been carried out.

Section 16: Other Information

List of abbreviations: ACGIH American Conference of Governmental Industrial Hygienists ADR European Agreement Concerning the International Carriage of Dangerous Goods by Road ALARA As Low As Is Reasonably Achievable AMU Atomic Mass Unit ANSI American National Standards Institute BLS Basic Life Support CAM Continuous Air Monitor CAS Chemical Abstracts Service (division of the American Chemical Society) CEN European Committee for Standardization CERCLA Comprehensive Environmental Response Compensation and Liability Act CLP Classification, Labelling and Packaging (European Union) CPR Controlled Products Regulations (Canada) CWA Clean Water Act (USA) DAC Derived Air Concentration (USA) DOE United States Department of Energy (USA) DOT United States Department of Transportation (USA) DSL Domestic Substances List (Canada) EC50 Half Maximal Effective Concentration EINECS European Inventory of Existing Commercial Chemical Substances EHS Environmentally Hazardous Substance ELINCS European List of Notified Chemical Substances EMS Emergency Response Procedures for Ships Carrying Dangerous Goods EPA Environmental Protection Agency (USA) EPCRA Emergency Planning and Community Right-To-Know Act (EPCRA) of 1986 GHS Globally Harmonized System HMIS Hazardous Materials Identification System (USA) IARC International Agency for Research on Cancer IATA International Air Transport Association IBC Intermediate Bulk Containers ICAO International Civil Aviation Organization IDLH Immediately Dangerous to Life or Health IMDG International Maritime Code for Dangerous Goods LC50 Lethal concentration, 50 percent LD50 Lethal dose, 50 percent LDLO Lethal Dose Low LOEC Lowest-Observed-Effective Concentration MARPOL International Convention for the Prevention of Pollution from Ships MSHA Mine Safety and Health Administration (USA) NCRP National Council on Radiation Protection & Measurements (USA)

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Safety Data Sheet for Gadolinium Oxide, Enriched Gadolinium Oxide According to ISO 11014:2010

First Print Date: 5-March-2015 Revision Date: 14-Aug-2019 Version: 1.1.1.

NDSL Non-Domestic Substances List (Canada) NFPA National Fire Protection Association (USA) NIOSH National Institute for Occupational Safety and Health (USA) NOEC No Observed Effect Concentration N.O.S. Not Otherwise Specified NRC Nuclear Regulatory Commission (USA) NTP National Toxicology Program (USA) OSHA Occupational Safety and Health Administration (USA) PBT Persistent Bioaccumulative and Toxic Chemical PEL Permissible Exposure Limit PIH Poisonous by Inhalation Hazard RCRA Resource Conservation and Recovery Act (USA) RCT Radiation Control Technician REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (Europe) RID Regulations Concerning the International Transport of Dangerous Goods by Rail RTECS Registry of Toxic Effects of Chemical Substances SARA Superfund Amendments and Reauthorization Act (USA) TDG Transportation of Dangerous Goods (Canada) TIH Toxic by Inhalation Hazard TLV Threshold Limit Value TPQ Threshold Planning Quantity TSCA Toxic Substances Control Act TWA Time Weighted Average UN United Nations (Number) VOC Volatile Organic Compound vPvB Very Persistent Very Bioaccumulative Chemical WGK Wassergefährdungsklassen (Germany: Water Hazard Classes) WHMIS Workplace Hazardous Materials Information System References: Not available. Full text of any H-statements not written out in full under Sections 2 to 15: None. Revision information: None. Training information: Follow training instructions when handling this material. Further Information: The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.

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