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Gadoteridol | SDS | CAS 120066-54-8 | Cayman Chemical | 33577 | English | 11/05/2025

Original Cayman Chemical safety data sheet for Gadoteridol. Original PDF retained without modification. Source collected on 2026-09-13.

Publisher: Cayman Chemical
Document type: SDS
Material: Gadoteridol
CAS: 120066-54-8
Product code: 33577
Language: English
Revision: 11/05/2025
Region: United States · OSHA
Pages: 7

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GdOrganic / coordination complexComposition not fully established

Why this document matches

Composition is not fully established. An unlisted element is not proof of absence.

Gd · Identification · Page 1

κN1,κN4,κN7,κN10,κO1,κO4,κO7]-gadolinium

Source and record details

Original record title: Gadoteridol — Safety Data Sheet — Cayman Chemical
Added to RESDS: 2026-09-13T12:49:01.000Z
Record updated: 2026-09-13T13:35:03.233Z
Original SDS revision: 11/05/2025
Original PDF SHA-256: fd44be4dbec5470875ef34afd174681d1ab384bb2f7b4780c3bbeaabb8e1b1d7

Original publisher/source document

Record dates describe this website, not the supplier’s revision date. Check the original PDF and obtain the applicable current version from its publisher.

Related indexes and classification basis

cas: 120066-54-8 — CAS printed in document metadata; may describe the product or a mixture component. (metadata association; confirm against the PDF)
element: Gadolinium — Identification: κN1,κN4,κN7,κN10,κO1,κO4,κO7]-gadolinium Page 1
material: Gadoteridol — Product identification: Gadoteridol (metadata association; confirm against the PDF)
publisher: Cayman Chemical — Product identification: Gadoteridol (metadata association; confirm against the PDF)

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Full document text

7 pages · Original document language

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Page 1

Page 1/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

1 Identification

· Product identifier

· Trade name: Gadoteridol · Synonym [10-[2-(hydrox y-κO )propyl]-1,4,7,10-tetraazac yc lododecane-1,4,7-triacetato(3-)- κN1,κN4,κN7,κN10,κO1,κO4,κO7]-gadolinium Gd-HP-D03A SQ 32,692 · CAS Number: 120066-54-8 · Other means of identification

· Article number: 33577 · Application of the substance / the mixture This product is for research use - Not for human or veterinary diagnostic or therapeutic use.

· Details of the supplier of the safety data sheet · Manufacturer/Supplier: Cayman Chemical Co. 1180 E. Ellsworth Rd. Ann Arbor, MI 48108 USA

· Information department: Product safety department · Emergency telephone number: During normal opening times: +1 (734) 971-3335 US/CANADA: 800-424-9300 Outside US/CANADA: 703-741-5970

* 2 Hazard(s) identification

· Classification of the substance or mixture The substance is not classified, according to the Globally Harmonized System (GHS).

· Label elements · GHS label elements None · Hazard pictograms None · Signal word None · Hazard statements None · Information pertaining to particular dangers for man and environment: · Classification system: · NFPA ratings (scale 0 - 4)

Health = 0

0 Fire = 0

0 0 Reactivity = 0

(Contd. on page 2)

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Page 2

Page 2/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 1) · HMIS-ratings (scale 0 - 4)

HEALTH 0 Health = 0 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

· Other hazards · Results of PBT and vPvB assessment · PBT: Not applicable. · vPvB: Not applicable. · Classification according to (d)(1)(ii) of § 1910.1200 The SDS issuer does not object to the classifications provided by importers or manufacturers of precursor products. · Hazards not otherwise classified There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard.

3 Composition/information on ingredients

· Chemical characterization: Substances · CAS No. Description 120066-54-8 Gadoteridol

4 First-aid measures

· Description of first aid measures · General information: No special measures required. · After inhalation: Supply fresh air; consult doctor in case of complaints. · After skin contact: Generally the product does not irritate the skin. · After eye contact: Rinse opened eye for several minutes under running water. · After swallowing: If symptoms persist consult doctor. · Most important symptoms and effects, both acute and delayed No further relevant information available. · Indication of any immediate medical attention and special treatment needed No further relevant information available.

5 Fire-fighting measures

· Extinguishing media · Suitable extinguishing agents: Use fire fighting measures that suit the environment. A solid water stream may be inefficient. · Special hazards arising from the substance or mixture No further relevant information available. · Advice for firefighters · Protective equipment: No special measures required.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required. · Environmental precautions: Do not allow to enter sewers/ surface or ground water. · Methods and material for containment and cleaning up: Pick up mechanically. (Contd. on page 3)

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Page 3

Page 3/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 2) · Protective Action Criteria for Chemicals · PAC-1: Substance is not listed. · PAC-2: Substance is not listed. · PAC-3: Substance is not listed. · Reference to other sections See Section 7 for information on safe handling. See Section 8 for information on personal protection equipment. See Section 13 for disposal information.

* 7 Handling and storage

· Precautions for safe handling No special measures required. · Information about protection against explosions and fires: No special measures required.

· Conditions for safe storage, including any incompatibilities · Storage: Store in accordance with information listed on the product insert. · Requirements to be met by storerooms and receptacles: No special requirements. · Information about storage in one common storage facility: Not required. · Further information about storage conditions: None. · Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Control parameters · Components with limit values that require monitoring at the workplace: Not required. · Additional information: The lists that were valid during the creation were used as basis.

· Exposure controls · Appropriate engineering controls No further data; see section 7. · Personal protective equipment: · General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed. · Breathing equipment: Not required. · Protection of hands: The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation · Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. · Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. · Eye protection: Not required.

US (Contd. on page 4)

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Page 4

Page 4/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 3)

* 9 Physical and chemical properties

· Information on basic physical and chemical properties · General Information · Physical state Solid · Color: Not determined. · Odor: Characteristic · Structural Formula C17H29GdN4O7 · Molecular Weight 558.7 g/mol · Storage Buffer · Odor threshold: Not determined. · Formulation · Melting point/Melting range: >225 °C (>437 °F) · Boiling point/Boiling range: Undetermined. · Flammability: Product is not flammable. · Explosion limits: · Lower: Not determined. · Upper: Not determined. · Flash point: Not applicable. · Decomposition temperature: Not determined. · pH-value: Not applicable. · Viscosity: · Kinematic: Not applicable. · SOLUBILITY PBS (pH 7.2): 10 mg/ml · Dynamic: Not applicable. · Solubility in / Miscibility with · Water: Not determined. · Partition coefficient (n-octanol/water): Not determined. · Vapor pressure: Not applicable. · Vapor pressure: · Density: Not determined. · Relative density Not determined. · Vapor density Not applicable. · Particle characteristics Not determined.

· Other information · Appearance: · Form: Solid · Important information on protection of health and environment, and on safety. · Ignition temperature: Not determined. · Danger of explosion: Product does not present an explosion hazard. · Change in condition · Evaporation rate Not applicable.

10 Stability and reactivity

· Reactivity No further relevant information available. · Chemical stability · Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. · Possibility of hazardous reactions No dangerous reactions known. (Contd. on page 5)

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Page 5

Page 5/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 4) · Conditions to avoid No further relevant information available. · Incompatible materials: acids · Hazardous decomposition products: carbon oxides, gadolinium oxides; nitrogen oxides

* 11 Toxicological information

· RTECS Number LW4430000 · Information on toxicological effects · Acute toxicity: · Primary irritant effect: · on the skin: No irritant effect. · on the eye: No irritating effect. · Sensitization: No sensitizing effects known. · Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification. · Interactive effects No interactive effects between components are known.

· Carcinogenic categories · IARC (International Agency for Research on Cancer) Substance is not listed. · NTP (National Toxicology Program) Substance is not listed. · OSHA-Ca (Occupational Safety & Health Administration) Substance is not listed. · Alternative sources for toxicological information No non-standard sources for toxicological information where used.

12 Ecological information

· Toxicity · Aquatic toxicity: No further relevant information available. · Persistence and degradability No further relevant information available. · Bioaccumulative potential No further relevant information available. · Mobility in soil No further relevant information available. · Results of PBT and vPvB assessment · PBT: Not applicable. · vPvB: Not applicable. · Other adverse effects · Additional ecological information: · General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.

13 Disposal considerations

· Waste treatment methods · Recommendation: Smaller quantities can be disposed of with household waste. (Contd. on page 6)

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Page 6

Page 6/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 5)

· Uncleaned packagings: · Recommendation: Disposal must be made according to official regulations.

* 14 Transport information

· UN-Number · DOT, IMDG, IATA not regulated

· UN proper shipping name · DOT, IMDG, IATA not regulated

· Transport hazard class(es)

· DOT, ADN, IMDG, IATA · Class not regulated

· Packing group · DOT, IMDG, IATA not regulated

· Environmental hazards: Not applicable.

· Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable.

· Special precautions for user Not applicable.

· UN "Model Regulation": not regulated

15 Regulatory information

· Safety, health and environmental regulations/legislation specific for the substance or mixture No further relevant information available. · Sara · Section 355 (extremely hazardous substances): Substance is not listed. · Section 313 (Specific toxic chemical listings): Substance is not listed. · TSCA (Toxic Substances Control Act): Substance is not listed. · Hazardous Air Pollutants Substance is not listed. · Chemicals known to cause cancer: Substance is not listed. · Chemicals known to cause reproductive toxicity for females: Substance is not listed. · Chemicals known to cause reproductive toxicity for males: Substance is not listed. · Chemicals known to cause developmental toxicity: Substance is not listed.

· Carcinogenic categories · EPA (Environmental Protection Agency) Substance is not listed. · TLV (Threshold Limit Value) Substance is not listed. · NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed. · Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

* 16 Other information

· Department issuing SDS: Environment protection department. · Contact: - · Date of previous version 02/16/2024 · Date of preparation 11/05/2025 (Contd. on page 7)

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Page 7

Page 7/7 Safety Data Sheet acc. to OSHA HCS

Date of issue: 11/05/2025 Revision date 11/05/2025

Trade name: Gadoteridol

(Contd. from page 6) · Abbreviations and acronyms: IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association CAS: Chemical Abstracts Service (division of the American Chemical Society) NFPA: National Fire Protection Association (USA) HMIS: Hazardous Materials Identification System (USA) PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative NIOSH: National Institute for Occupational Safety OSHA: Occupational Safety & Health TLV: Threshold Limit Value PEL: Permissible Exposure Limit REL: Recommended Exposure Limit · * Data compared to the previous version altered.

61.0.30