Holmium oxide in perchloric acid solution SDS

Date of Issue: 12 April 2016 SAFETY DATA SHEET

1. SUBSTANCE AND SOURCE IDENTIFICATION Product Identifier SRM Number: 2034 SRM Name: Holmium Oxide Solution Wavelength Standard (240 nm to 650 nm) Other Means of Identification: Not applicable. Recommended Use of This Material and Restrictions of Use This Standard Reference Material (SRM) is a certified transfer standard intended for the verification and calibration of the wavelength scale of ultraviolet and visible absorption spectrophotometers having nominal spectral bandwidths not exceeding 3 nm. A unit of SRM 2034 consists of an aqueous solution containing 4 % (mass fraction) holmium oxide (Ho2O3) in 10 % (volume fraction) perchloric acid (HClO4). The solution is contained in a flame-sealed, nonfluorescent, fused-silica cuvette of optical quality (parallel to ≈ 0.9 mrad and flat to ≈ 1 µm). Company Information National Institute of Standards and Technology Standard Reference Materials Program 100 Bureau Drive, Stop 2300 Gaithersburg, Maryland 20899-2300

Telephone: 301-975-2200 Emergency Telephone ChemTrec: FAX: 301-948-3730 1-800-424-9300 (North America) E-mail: SRMMSDS@nist.gov +1-703-527-3887 (International) Website: http://www.nist.gov/srm

2. HAZARDS IDENTIFICATION

Classification Physical Hazard: Not classified. Health Hazard: Skin Corrosion/Irritation Category 1B Serious Eye Damage/Irritation Category 1 Label Elements Symbol

Signal Word DANGER Hazard Statement(s) H314 Causes severe skin burns and eye damage. Precautionary Statement(s) P260 Do not breathe fumes, mists, vapors, spray. P264 Wash hands thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves, protective clothing, eye protection. P301 + P330 + P331 If swallowed: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 If on skin (or hair): Remove immediately all contaminated clothing. Rinse skin with water. P304 + P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305 + P351 + P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. SRM 2034 Page 1 of 6

P310 Immediately call a doctor. P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents and container according to local regulations. Hazards Not Otherwise Classified: Not applicable. Ingredients(s) with Unknown Acute Toxicity: Not applicable.

3. COMPOSITION AND INFORMATION ON HAZARDOUS INGREDIENTS

Substance: Perchloric acid/holmium oxide solution Other Designations: Perchloric acid (dioxonium perchlorate; perchloric acid solution; perchloric acid; HClO4) Holmium oxide (Ho2O3; diholmium trioxide; holmium (3+) oxide; holmium sesquioxide; holmium trioxide) Components are listed in compliance with OSHA’s 29 CFR 1910.1200; for the actual values see the Certificate of Analysis. Hazardous Component(s) CAS Number EC Number Nominal Mass Concentration (EINECS) (%) Perchloric acid 7601-90-3 231-512-4 7 Holmium oxide 12055-62-8 234-015-3 4 Non-Hazardous Component(s) Water 7732-18-5 231-791-2 89

4. FIRST AID MEASURES

Description of First Aid Measures: Inhalation: If adverse effects occur, remove to uncontaminated area. If not breathing, give artificial respiration or oxygen by qualified personnel. Seek immediate medical attention. Skin Contact: Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get immediate medical attention. Thoroughly clean and dry contaminated clothing before reuse. Destroy contaminated shoes. Eye Contact: Immediately flush eyes, including under the eyelids with copious amounts of water for at least 15 minutes. Seek immediate medical attention. Ingestion: Contact a poison control center immediately for instructions. Do not induce vomiting. Give water to rinse out mouth. Never give liquids to a person with reduced awareness or becoming unconscious. If vomiting occurs, keep head lower than hips to prevent aspiration. If not breathing, give artificial respiration by qualified personnel. Seek immediate medical attention. Most Important Symptoms/Effects, Acute and Delayed: Acid burns to skin, eyes, and lungs. Indication of any immediate medical attention and special treatment needed, if necessary: If any of the above symptoms are present, seek immediate medical attention.

5. FIRE FIGHTING MEASURES

Fire and Explosion Hazards: Negligible fire hazard. See Section 9, “Physical and Chemical Properties” for flammability properties. Extinguishing Media: Suitable: Use extinguishing media appropriate to the surrounding fire. Unsuitable: None listed. Specific Hazards Arising from the Chemical: Thermal decomposition will form hydrogen chloride and oxides of chlorinated compounds. Special Protective Equipment and Precautions for Fire-Fighters: Avoid inhalation of material or combustion byproducts. Wear full protective clothing and NIOSH approved self-contained breathing apparatus (SCBA). NFPA Ratings (0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe) Health = 3 Fire = 0 Reactivity = 0

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6. ACCIDENTAL RELEASE MEASURES

Personal Precautions, Protective Equipment and Emergency Procedures: Immediately contact emergency personnel. Keep unnecessary personnel away. Use suitable protective equipment; see Section 8, “Exposure Controls and Personal Protection”. Methods and Materials for Containment and Clean up: Do not touch spilled material. Notify safety personnel of spills. Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. Isolate hazard area and deny entry.

7. HANDLING AND STORAGE

Safe Handling Precautions: See Section 8, “Exposure Controls and Personal Protection”. Handle glass ampoules with care. Storage: Store and handle in accordance with all current regulations and standards. Keep separated from incompatible substances (See Section 10, “Stability and Reactivity”).

8. EXPOSURE CONTROLS AND PERSONAL PROTECTION

Exposure Limits: No occupational exposure limits established for the main components (perchloric acid; holmium oxide) or the solution. Engineering Controls: Provide local exhaust or process enclosure ventilation system. Ensure compliance with applicable exposure limits. Personal Protection: In accordance with OSHA 29 CFR 1910.132, subpart I, wear appropriate Personal Protective Equipment (PPE) to minimize exposure to this material. Respiratory Protection: If workplace conditions warrant a respirator, a respiratory protection program that meets OSHA 29CFR 1910.134 must be followed. Refer to NIOSH 42 CFR 84 for applicable certified respirators. Eye/Face Protection: Wear splash resistant safety goggles with a face shield. An eyewash station should be readily available near areas of use. Skin and Body Protection: Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Chemical-resistant gloves should be worn at all times when handling chemicals.

9. PHYSICAL AND CHEMICAL PROPERTIES

NOTE: The physical and chemical data provided are for the pure components. No physical or chemical data are available for this solution. The actual behavior of the solution may differ from the individual components. Descriptive Properties: Perchloric Acid Holmium Oxide (7 % mass fraction) (4 % mass fraction) Appearance (physical state, color, etc.): clear, colorless solution off-white to orange solid; hygroscopic Molecular Formula: HClO4 Ho2O3 Molar Mass (g/mol): 100.46 377.86 Odor: odorless odorless Odor threshold: not available not available pH: acidic not available Evaporation rate: not available not available Melting point/freezing point: –4 °C (24.8 °F) 2360 °C (4280 °F) Relative Density (g/L) as specific gravity 1.764 at 22 °C 8.4 (water = 1): Vapor Pressure (mmHg): not available not available Vapor Density (air = 1): 3.46 not available Viscosity (cP): not available not available Solubility(ies): soluble in water insoluble in water Partition coefficient (n-octanol/water): not available not available

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Thermal Stability Properties: Perchloric Acid Holmium Oxide (7 % mass fraction) (4 % mass fraction) Autoignition Temperature (ºC): not available not available Thermal Decomposition (ºC): not available not available Initial boiling point and boiling range: 39 °C at 56 mmHg not available Explosive Limits, LEL (Volume %): not available not available Explosive Limits, UEL (Volume %): not available not available Flash Point (ºC): not available not available Flammability (solid, gas): not applicable not available

10. STABILITY AND REACTIVITY

Reactivity: Stable at normal temperatures and pressure. Stability: X Stable Unstable Possible Hazardous Reactions: None listed. Conditions to Avoid: Contact with combustible or incompatible materials. Incompatible Materials: Incompatible with acids, combustible materials, halo carbons, bases, oxidizing materials, metals, halogens, metal salts, metal oxides. Fire/Explosion Information: See Section 5, “Fire Fighting Measures”. Hazardous Decomposition: Thermal decomposition will form hydrogen chloride and oxides of chlorinated compounds. Hazardous Polymerization: Will Occur X Will Not Occur

11. TOXICOLOGICAL INFORMATION

Route of Exposure: X Inhalation X Skin X Ingestion Symptoms Related to the Physical, Chemical and Toxicological Characteristics: Burning pain and severe skin corrosion and eye damage. Potential Health Effects (Acute, Chronic and Delayed): Inhalation: Inhalation of perchloric acid may damage the mucous membranes and upper respiratory tract. Short term exposure may cause irritation, headache, dizziness, and nausea. Long term exposure to acid fumes may cause damage to teeth, bronchial irritation, chronic cough, bronchial pneumonia, and gastrointestinal disturbances. Skin Contact: Perchloric acid may cause skin burns and irritation. Severity of the damage depends on the concentration and duration of exposure. Effects of acid burns may be delayed. Eye Contact: Perchloric acid may cause eye irritation or corneal burns. Severity of the damage depends on the concentration and duration of exposure. Ingestion: Ingestion of this material is unlikely under normal conditions of use. If ingested, perchloric acid can cause burns and damage to the gastrointestinal tract. Numerical Measures of Toxicity: Acute Toxicity: Not classified. Perchloric acid, Rat, Oral LD50: 1100 mg/kg; Skin Corrosion/Irritation: This SRM contains >1 % of perchloric acid and it is classified as Category 1B. Serious Eye Damage/Irritation: This SRM contains >1 % of perchloric acid and it is classified as Category 1. Respiratory Sensitization: No data available; not classified. Skin Sensitization: No data available; not classified. Germ Cell Mutagenicity: No data available; not classified.

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Carcinogenicity: Not classified. Listed as a Carcinogen/Potential Carcinogen Yes X No Perchloric acid and holmium oxide are not classified as either a carcinogen or potential carcinogen by OSHA, IARC, or NTP. Reproductive Toxicity: No data available; not classified. Specific Target Organ Toxicity, Single Exposure: No data available; not classified. Specific Target Organ Toxicity, Repeated Exposure: No data available; not classified. Aspiration Hazard: No data available; not classified.

12. ECOLOGICAL INFORMATION

Ecotoxicity Data: No data available. Persistence and Degradability: No data available. Bioaccumulative Potential: No data available. Mobility in Soil: No data available. Other Adverse effects: No data available.

13. DISPOSAL CONSIDERATIONS

Waste Disposal: Dispose of waste in accordance with all applicable federal, state, and local regulations. Perchloric acid is subject to disposal regulations: U.S. EPA 40 CFR 262: D001 and D003.

14. TRANSPORTATION INFORMATION

U.S. DOT and IATA: UN1760, Corrosive liquid, n.o.s. (contains perchloric acid), Hazard Class 8, Packing Group II, Excepted Quantities E2.

15. REGULATORY INFORMATION

U.S. Regulations: CERCLA Sections 102a/103 (40 CFR 302.4): Not regulated. SARA Title III Section 302 (40 CFR 355.30): Not regulated. SARA Title III Section 304 (40 CFR 355.40): Not regulated. SARA Title III Section 313 (40 CFR 372.65): Not regulated. OSHA Process Safety (29 CFR 1910.119): Perchloric acid, 5000 lbs TQ (≥60 % by weight) SARA Title III Sections 311/312 Hazardous Categories (40 CFR 370.21): ACUTE HEALTH: Yes CHRONIC HEALTH: No FIRE: No REACTIVE: No PRESSURE: No State Regulations: California Proposition 65: Not listed. U.S. TSCA Inventory: Perchloric acid and holmium oxide are listed. TSCA 12(b), Export Notification: Not listed. Canadian Regulations: WHMIS Information is not provided for this material.

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16. OTHER INFORMATION

Issue Date: 12 April 2016 Sources: ChemAdvisor, Inc., SDS Perchloric Acid, 09 December 2015. ChemAdvisor, Inc., SDS Holmium Oxide, 09 December 2015.

Key of Acronyms: ACGIH American Conference of Governmental Industrial NRC Nuclear Regulatory Commission Hygienists ALI Annual Limit on Intake NTP National Toxicology Program CAS Chemical Abstracts Service OSHA Occupational Safety and Health Administration CERCLA Comprehensive Environmental Response, PEL Permissible Exposure Limit Compensation, and Liability Act CFR Code of Federal Regulations RCRA Resource Conservation and Recovery Act DOT Department of Transportation REL Recommended Exposure Limit EC50 Effective Concentration, 50% RM Reference Material EINECS European Inventory of Existing Commercial RQ Reportable Quantity Chemical Substances EPCRA Emergency Planning and Community Right-to-Know RTECS Registry of Toxic Effects of Chemical Substances Act IARC International Agency for Research on Cancer SARA Superfund Amendments and Reauthorization Act IATA International Air Transport Agency SCBA Self-Contained Breathing Apparatus IDLH Immediately Dangerous to Life and Health SRM Standard Reference Material LC50 Lethal Concentration, 50 % STEL Short Term Exposure Limit LD50 Lethal Dose, 50 % TLV Threshold Limit Value LEL Lower Explosive Limit TPQ Threshold Planning Quantity MSDS Material Safety Data Sheet TSCA Toxic Substances Control Act NFPA National Fire Protection Association TWA Time Weighted Average NIOSH National Institute for Occupational Safety and Health UEL Upper Explosive Limit NIST National Institute of Standards and Technology WHMIS Workplace Hazardous Materials Information System n.o.s. Not Otherwise Specified

Disclaimer: Physical and chemical data contained in this SDS are provided only for use in assessing the hazardous nature of the material. The SDS was prepared carefully, using current references; however, NIST does not certify the data in the SDS. The certified values for this material are given in the NIST Certificate of Analysis. Users of this SRM should ensure that the SDS in their possession is current. This can be accomplished by contacting the SRM Program: telephone (301) 975-2200; fax (301) 948-3730; e-mail srmmsds@nist.gov; or via the Internet at http://www.nist.gov/srm.

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