Lanthanum-138 SDS

Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Section 1: Identification of the Substance/Mixture and of the Company/Undertaking

Product Identifier: Identification as on the label/Trade name: Lanthanum Oxide. Molecular weight: 325.81 Chemical formula: La2O3 Synonyms: Lanthanum(III) Oxide.

Details of the supplier of the Safety Data Sheet: Neonest AB Storgatan 70C, Solna SE-17152 Sweden

Contact details: +46-76-219-9731

24-hour Emergency Contact: Swedish Poisons Centre Phone: 112 - Ask for Poisons Information, 112 – begär Giftinformation.

Other International Contacts: CHEMTREC 24-hour: +1-703-741-5500 (US + Worldwide) NHS: 111 (UK) Charite: +49 30 450 531 000 (Netherlands) INTCF: +34 917689800 (Spain) CapTv: +33 1 40 05 48 48 (France)

Section 2: Hazards Identification

Classification of the substances or mixture: The mixture is classified according to: Regulation EC 1272/2008 [EU-GHS/CLP]

Hazard classes/Hazard categories: Hazard statement: Skin Irritant (Category 2) H315 Eye Irritant (Category 2) H319 STOT SE (Category 3) H335

Label elements: Hazard pictograms:

Signal Words: Warning.

Safety Data Sheet (SDS) for Lanthanum Oxide, Enriched Lanthanum Oxide https://www.buyisotope.com Page 1/9

Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Hazard Statements: H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary Statements: P261 Avoid breathing dust/fume/gas/mist/vapors/spray. P280 Wear protective gloves/ protective clothing/eye protection/face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. Other hazards: None known.

Section 3: Composition/Information on Ingredients

Substance/Mixture: Substance. Ingredients:

CAS-No. Molecular Concentration Classification Substance name (IUPAC/EC) EC-No. weight % by weight EC1272/2008 1312-81-8 Lanthanum oxide 325.81 >99% GHS07 215-200-5

For explanation of abbreviations see Section 16.

Section 4: First-Aid Measures

Description of first aid measures: In case of inhalation: If breathing difficulties develop, move victim away from exposure and into fresh air. If not breathing, give artificial respiration. In case of skin contact: May cause skin irritation. Wash off with soap and plenty of water. In case of eye contact: May cause eye irritation. Flush eyes with water as a precaution. In case of ingestion: Never give anything by mouth to an unconscious person. Rinse mouth with water.

Most important symptoms and effects, both acute and delayed: General advice: Take the victim out of the contaminated area. Remove contaminated clothing immediately and dispose of safely. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing becomes difficult, call a physician. Eyes: In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. Skin contact: In case of contact, immediately wash skin with soap and copious amounts of water. Ingestion: If swallowed, wash out mouth with water provided person is conscious. Do NOT induce vomiting. Call a physician.

Safety Data Sheet (SDS) for Lanthanum Oxide, Enriched Lanthanum Oxide https://www.buyisotope.com Page 2/9

Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Indication of any immediate medical attention and special treatment needed: Treat symptomatically. Show this safety data sheet to a physician or emergency room.

Section 5: Fire-Fighting Measures

Extinguisher media: Suitable extinguisher media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Unsuitable extinguishing media: None known. Special hazards arising from the mixture: Lanthanum oxides. Advice for fire-fighters: Wear self-contained breathing apparatus for firefighting if necessary. Further information: Standard procedure for chemical fires. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Personal precautions: Avoid dust formation. Avoid breathing vapours, mist or gas. For personal protection see section 8. Remove all sources of ignition. Environmental precautions: No special environmental precautions required.

Methods for containment and cleaning up: Methods for cleaning up: Collect with an electrically protected vacuum cleaner or by wet-brushing, place in a suitable, closed containers and hold for disposal according to local regulations. Avoid raising dust. Elimination of recovered materials: Deliver to the Environmental service of the factory or to any specialized and approved disposal company.

Reference to other sections: Treat recovered material as described in the section "Disposal considerations", section 13.

Section 7: Handling and Storage

Precautions for safe handling: Advice on safe handling: User Exposure: Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure. Take precautionary measures against electrostatic loading. Provide appropriate exhaust ventilation at places where dust is formed. Keep away from sources of ignition - No smoking. Hygiene measures: Do not eat, drink or smoke when using this product.

Conditions for safe storage, including incompatibilities: Requirements for storage areas and containers: Keep tightly closed in a dry and well-ventilated place. Air and moisture sensitive. Store in cool place. Store under inert gas. Keep away from oxidising agents, strongly alkaline and strongly acid materials in order to avoid exothermic reactions. Advised packaging material: Glass, polyethylene, polypropylene.

Section 8: Exposure Controls/Personal Protection

Control parameters:

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Occupational exposure limits: No data available. Exposure controls: Appropriate engineering controls: Safety shower and eye bath. Mechanical exhaust required.

Individual protection measures, such as personal protective equipment: Eye/face protection: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Hand protection: Use chemical resistant gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Body protection: Wear appropriate protective clothing to prevent skin exposure. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection: Respiratory protection is not required. Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Section 9: Physical and Chemical Properties

Information on basic physical and chemical properties Appearance (form): Powder. Colour: White. Odour: Odourless. Odour threshold: No data available. Molecular Weight: 325.81 pH (concentration): No data available. Melting point/range (°C): 2307 °C Boiling point/range (°C): 4200 °C Freezing point (°C): No data available. Flash point (°C): No data available. Evaporation rate: No data available. Flammability (solid, gas): No data available. Ignition temperature (°C): No data available. Upper/lower flammability/explosive limits: No data available. Vapour pressure (20 °C): No data available Vapour density: No data available. Relative density (25 °C): 6.51 g/cm3 Water solubility (g/L) at 20 °C: 0,00007 g/l - OECD Test Guideline 105 - insoluble. n-Octanol/Water partition coefficient: No data available. Auto-ignition temperature: No data available. Decomposition temperature: No data available. Viscosity, dynamic (mPa s): No data available. Explosive properties: No data available. Oxidising properties: No data available.

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Section 10: Stability and Reactivity

Reactivity: No data available. Chemical stability: Stable under recommended storage conditions. Possibility of hazardous reactions: No data available. Conditions to avoid: Avoid moisture. Incompatible materials: Strong acids, Strong oxidizing agents, Carbon dioxide (CO2). Water. Hazardous decomposition products: Hazardous decomposition products formed under fire conditions - Lanthanum oxides. Metal oxide fume. Other decomposition products - No data available.

Section 11: Toxicological Information

Information on toxicological effects: Acute toxicity LD50 Oral - Rat - male and female - >= 10.000 mg/kg (OECD Test Guideline 401) LD50 Oral - Rat - > 9.968 mg/kg Remarks: (RTECS) LC0 Inhalation - Rat - male and female - 4 h - >= 5,3 mg/l (OECD Test Guideline 403) Skin corrosion/irritation Skin - Rabbit. Result: No skin irritation - 24 h Remarks: (ECHA) Serious eye damage/eye irritation Eyes - Rabbit. Result: Mild eye irritation (Draize Test) Respiratory or skin sensitisation - Guinea pig. Result: Does not cause skin sensitisation. (Maximisation Test) Germ cell mutagenicity Ames test S. typhimurium Result: negative Classification according to GHS (1272/2008/EG, CLP) Skin corrosion/irritation: Not classified based on available information. Serious eye damage/eye irritation: Not classified based on available information. Respiratory or skin sensitisation: Not classified based on available information. Germ cell mutagenicity: Not classified based on available information. Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as a probable, possible or confirmed human carcinogen by IARC. NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity:

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Not classified based on available information. Specific target organ toxicity – single exposure (STOT): Not classified based on available information. Specific target organ toxicity (STOT) – repeated exposure: Not classified based on available information. Aspiration toxicity: Not classified based on available information.

Section 12: Ecological Information

Toxicity: Toxicity to daphnia and other aquatic invertebrates. Immobilization NOEC - Daphnia magna (Water flea) - >= 100 mg/l - 48 h (OECD Test Guideline 202) Persistence and degradability: The methods for determining the biological degradability are not applicable to inorganic substances. Bioaccumulative potential: No data available. Mobility in soil: No data available. Results of PBT& vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Other adverse effects: No data available.

Section 13: Disposal Considerations

Waste treatment methods: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Leave chemicals in original containers. Observe all local and national environmental regulations.

Section 14: Transport Information

UN number: Not regulated as a dangerous good. UN proper shipping name: Not regulated as a dangerous good. Transport hazard class(es): Not regulated as a dangerous good. Packing group: Not regulated as a dangerous good. Environmental hazards: Not regulated as a dangerous good. Special precautions for user: Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR. Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable

Section 15: Regulatory Information

EU regulations: Regulation (EC) No. 1005/2009 on substances that deplete the ozone layer, Annex I and II, as amended Not listed. Regulation (EC) No. 850/2004 on persistent organic pollutants, Annex I Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 1 as amended Not listed.

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 2 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex I, Part 3 as amended Not listed. Regulation (EU) No. 649/2012 concerning the export and import of dangerous chemicals, Annex V as amended Not listed. Regulation (EC) No. 166/2006 Annex II Pollutant Release and Transfer Registry Not listed. Regulation (EC) No. 1907/2006, REACH Article 59(10) Candidate List as currently published by ECHA Not listed.

Authorisations: Regulation (EC) No. 1907/2006, REACH Annex XIV Substances subject to authorization, as amended Not listed.

Restrictions on use: Regulation (EC) No. 1907/2006 Annex XVII Substances subject to restriction on marketing and use Not regulated. Regulation (EC) No. 1907/2006, REACH Annex XVII Substances subject to restriction on marketing and use as amended Not listed. Directive 2004/37/EC on the protection of workers from the risks related to exposure to carcinogens and mutagens at work Not regulated. Directive 92/85/EEC: on the safety and health of pregnant workers and workers who have recently given birth or are breastfeeding. Not regulated.

Other EU regulations: Directive 2012/18/EU on major accident hazards involving dangerous substances Not listed. Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Always applicable. Directive 94/33/EC on the protection of young people at work Not listed.

Other regulations: The product is classified and labelled in accordance with EC directives or respective national laws. This Safety Data Sheet complies with the requirements of Regulation (EC) No 1907/2006, as amended. SARA 302 Components: No chemicals in this material are subject to the reporting requirements of SARA Title III,

Section 302.

SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards: No SARA Hazards. Massachusetts Right to Know Components: Magnesium oxide / CAS No. 1309-48-4 / Revision Date March 1, 2007

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

Pennsylvania Right to Know Components: Magnesium oxide / CAS No. 1309-48-4 / Revision Date March 1, 2007 New Jersey Right to Know Components: Magnesium oxide / CAS No. 1309-48-4 / Revision Date March 1, 2007 California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm. National regulations: Follow national regulation for work with chemical agents. Chemical safety assessment: No Chemical Safety Assessment has been carried out.

Section 16: Other Information

List of abbreviations: ACGIH American Conference of Governmental Industrial Hygienists ADR European Agreement Concerning the International Carriage of Dangerous Goods by Road ALARA As Low As Is Reasonably Achievable AMU Atomic Mass Unit ANSI American National Standards Institute BLS Basic Life Support CAM Continuous Air Monitor CAS Chemical Abstracts Service (division of the American Chemical Society) CEN European Committee for Standardization CERCLA Comprehensive Environmental Response Compensation and Liability Act CLP Classification, Labelling and Packaging (European Union) CPR Controlled Products Regulations (Canada) CWA Clean Water Act (USA) DAC Derived Air Concentration (USA) DOE United States Department of Energy (USA) DOT United States Department of Transportation (USA) DSL Domestic Substances List (Canada) EC50 Half Maximal Effective Concentration EINECS European Inventory of Existing Commercial Chemical Substances EHS Environmentally Hazardous Substance ELINCS European List of Notified Chemical Substances EMS Emergency Response Procedures for Ships Carrying Dangerous Goods EPA Environmental Protection Agency (USA) EPCRA Emergency Planning and Community Right-To-Know Act (EPCRA) of 1986 GHS Globally Harmonized System HMIS Hazardous Materials Identification System (USA) IARC International Agency for Research on Cancer IATA International Air Transport Association IBC Intermediate Bulk Containers ICAO International Civil Aviation Organization IDLH Immediately Dangerous to Life or Health IMDG International Maritime Code for Dangerous Goods LC50 Lethal concentration, 50 percent LD50 Lethal dose, 50 percent LDLO Lethal Dose Low LOEC Lowest-Observed-Effective Concentration MARPOL International Convention for the Prevention of Pollution from Ships

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Safety Data Sheet for Lanthanum Oxide, Enriched Lanthanum Oxide According to ISO 11014:2010

First Print Date: 5-Mar-2015 Revision Date: 08-Jul-2020 Version: 1.1.1.

MSHA Mine Safety and Health Administration (USA) NCRP National Council on Radiation Protection & Measurements (USA) NDSL Non-Domestic Substances List (Canada) NFPA National Fire Protection Association (USA) NIOSH National Institute for Occupational Safety and Health (USA) NOEC No Observed Effect Concentration N.O.S. Not Otherwise Specified NRC Nuclear Regulatory Commission (USA) NTP National Toxicology Program (USA) OSHA Occupational Safety and Health Administration (USA) PBT Persistent Bioaccumulative and Toxic Chemical PEL Permissible Exposure Limit PIH Poisonous by Inhalation Hazard RCRA Resource Conservation and Recovery Act (USA) RCT Radiation Control Technician REACH Registration, Evaluation, Authorisation and Restriction of Chemicals (Europe) RID Regulations Concerning the International Transport of Dangerous Goods by Rail RTECS Registry of Toxic Effects of Chemical Substances SARA Superfund Amendments and Reauthorization Act (USA) TDG Transportation of Dangerous Goods (Canada) TIH Toxic by Inhalation Hazard TLV Threshold Limit Value TPQ Threshold Planning Quantity TSCA Toxic Substances Control Act TWA Time Weighted Average UN United Nations (Number) VOC Volatile Organic Compound vPvB Very Persistent Very Bioaccumulative Chemical WGK Wassergefährdungsklassen (Germany: Water Hazard Classes) WHMIS Workplace Hazardous Materials Information System References: Not available. Full text of any H-statements not written out in full under Sections 2 to 15: None. Revision information: None. Training information: Follow training instructions when handling this material. Further Information: The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.

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