Gadolinium(III) acetylacetonate hydrate SDS

SAFETY DATA SHEET Revision Date 09/18/2019Version 6.0 Print Date 10/22/2019

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers

Product name : Gadolinium(III) acetylacetonate hydrate

Product Number : 331716 Brand : Aldrich CAS-No. : 64438-54-6

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses : Laboratory chemicals, Synthesis of substances

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich Inc. 3050 Spruce Street ST. LOUIS MO 63103 UNITED STATES

Telephone : +1 314 771-5765 Fax : +1 800 325-5052

1.4 Emergency telephone number

Emergency Phone # : +1-703-527-3887

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)

Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335

For the full text of the H-Statements mentioned in this Section, see Section 16.

2.2 GHS Label elements, including precautionary statements

Pictogram

Signal word Warning

Hazard statement(s) H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.

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Precautionary statement(s) P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER/doctor if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none

SECTION 3: Composition/information on ingredients

3.1 Substances Synonyms : 2,4-Pentanedionegadolinium(III) derivative Gd(acac)3

Formula : C15H21GdO6 · xH2O Molecular weight : 454.57 g/mol CAS-No. : 64438-54-6 EC-No. : 238-186-2

Component Classification Concentration

Gadolinium(III) acetylacetonate hydrate Skin Irrit. 2; Eye Irrit. 2A; <= 100 % STOT SE 3; H315, H319, H335

For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first aid measures

General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.

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If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact Wash off with soap and plenty of water. Consult a physician.

In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture Carbon oxides, gadolinium oxides

5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.

5.4 Further information No data available

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

6.4 Reference to other sections For disposal see section 13.

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SECTION 7: Handling and storage

7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): 13: Non Combustible Solids

7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Components with workplace control parameters Contains no substances with occupational exposure limit values.

8.2 Exposure controls

Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Body Protection Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure Do not let product enter drains.

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SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

a) Appearance Form: solid

b) Odour No data available

c) Odour Threshold No data available

d) pH No data available

e) Melting Melting point/range: 143 °C (289 °F) - dec. point/freezing point

f) Initial boiling point No data available and boiling range

g) Flash point ()No data available

h) Evaporation rate No data available

i) Flammability (solid, No data available gas)

j) Upper/lower No data available flammability or explosive limits

k) Vapour pressure No data available

l) Vapour density No data available

m) Relative density No data available

n) Water solubility No data available

o) Partition coefficient: No data available n-octanol/water

p) Auto-ignition No data available temperature

q) Decomposition No data available temperature

r) Viscosity No data available

s) Explosive properties No data available

t) Oxidizing properties No data available

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Reactivity No data available

10.2 Chemical stability Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions No data available

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10.4 Conditions to avoid No data available

10.5 Incompatible materials Strong oxidizing agents

10.6 Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, gadolinium oxides Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity No data available Dermal: No data available No data available

Skin corrosion/irritation No data available

Serious eye damage/eye irritation No data available

Respiratory or skin sensitisation No data available

Germ cell mutagenicity No data available

Carcinogenicity

IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.

NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is on OSHA’s list of regulated carcinogens.

Reproductive toxicity No data available Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.

Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation.

Specific target organ toxicity - repeated exposure No data available

Aspiration hazard No data available

Additional Information RTECS: Not available

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May liberate 2,4-pentanedione upon decomposition. 2,4-Pentanedione has the following toxicological hazards: toxic, irritant, neurological hazard, teratogen, possible mutagen, target organ - thymus. In humans, 2,4-pentanedione is reported to cause contact dermatitis and contact urticaria.

Stomach - Irregularities - Based on Human Evidence Stomach - Irregularities - Based on Human Evidence

SECTION 12: Ecological information

12.1 Toxicity No data available

12.2 Persistence and degradability No data available

12.3 Bioaccumulative potential No data available

12.4 Mobility in soil No data available

12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material.

Contaminated packaging Dispose of as unused product.

SECTION 14: Transport information

DOT (US) Not dangerous goods

IMDG Not dangerous goods

IATA Not dangerous goods

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SECTION 15: Regulatory information

SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III,

Section 302.

SARA 313 Components This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards Acute Health Hazard, Chronic Health Hazard

Massachusetts Right To Know Components No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components Gadolinium(III) acetylacetonate hydrate CAS-No. Revision Date 64438-54-6

New Jersey Right To Know Components Gadolinium(III) acetylacetonate hydrate CAS-No. Revision Date 64438-54-6

California Prop. 65 Components This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

SECTION 16: Other information

Further information Copyright 2018 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

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Version: 6.0 Revision Date: 09/18/2019 Print Date: 10/22/2019

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The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the US and Canada