Gadolinium Standard: 1000 μg/mL Gd in 5% HNO3 [500ml bottle] SDS

SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

Revision date 25-Jun-2024 Revision Number 1

1. Identification

Product identifier

Product Name Gadolinium Standard: 1000 μg/mL Gd in 5% HNO3 [500ml bottle]

Other means of identification

Product Code(s) 5190-8456

Synonyms None

Recommended use of the chemical and restrictions on use

Recommended use Reagents and Standards for Analytical Chemical Laboratory Use

Restrictions on use Not to be used for human or animal consumption

Details of the supplier of the safety data sheet

Supplier Address

Agilent Technologies, Inc. 5301 Stevens Creek Blvd Santa Clara, CA 95051, USA

800-227-9770

E-mail pdl-msds_author@agilent.com

Emergency telephone number

Emergency Telephone CHEMTREC®: 1-800-424-9300

2. Hazard(s) identification

Classification

Classified according to OSHA.

Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 1 Corrosive to metals Category 1

Hazards not otherwise classified (HNOC)

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Not applicable

Label elements Danger

Hazard statements Classified according to OSHA. Causes skin irritation Causes serious eye damage May be corrosive to metals

Precautionary Statements - Prevention Wash face, hands and any exposed skin thoroughly after handling Keep only in original packaging Wear protective gloves/eye protection/face protection

Precautionary Statements - Response

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor IF ON SKIN: Wash with plenty of water and soap If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash it before reuse Absorb spillage to prevent material damage

Precautionary Statements - Storage Store in corrosion resistant container with a resistant inner liner

Other information No information available.

3. Composition/information on ingredients

Substance

Not applicable.

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Mixture

Chemical nature aqueous solution.

Chemical name CAS No. Weight-% Trade secret Nitric Acid 7697-37-2 3 - <5 *

Additional information The concentration of the acid stated in this SDS is calculated as an absolute mass concentration (%w/v). This is less than the acid concentration stated on the product label and COA, which reflects a percent value of the commercially available concentrated aqueous form of the acid.

4. First-aid measures

Description of first aid measures

General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.

Inhalation Remove to fresh air. Get medical attention immediately if symptoms occur.

Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Keep eye wide open while rinsing. Do not rub affected area. Get immediate medical attention.

Skin contact Wash off immediately with soap and plenty of water for at least 15 minutes. Get medical attention if irritation develops and persists.

Ingestion Rinse mouth. Never give anything by mouth to an unconscious person. Do NOT induce vomiting. Call a physician.

Self-protection of the first aider Avoid contact with skin, eyes or clothing. Wear personal protective clothing (see section 8).

Most important symptoms and effects, both acute and delayed

Symptoms Burning sensation.

Indication of any immediate medical attention and special treatment needed

Note to physicians Treat symptomatically.

5. Fire-fighting measures

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient.

Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams.

Specific hazards arising from the No information available. chemical

Explosion data Sensitivity to mechanical impact None.

Sensitivity to static discharge None.

Special protective equipment and Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. precautions for fire-fighters Use personal protection equipment.

6. Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal precautions Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required.

Other information Refer to protective measures listed in Sections 7 and 8.

Methods and material for containment and cleaning up

Methods for containment Prevent further leakage or spillage if safe to do so.

Methods for cleaning up Pick up and transfer to properly labeled containers.

7. Handling and storage

Precautions for safe handling

Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Take off contaminated clothing and wash before reuse.

Conditions for safe storage, including any incompatibilities

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Storage Conditions Please refer to the manufacturer's certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. Keep containers tightly closed in a dry, cool and well-ventilated place. Protect from moisture. Store locked up. Keep out of the reach of children. Store away from other materials.

8. Exposure controls/personal protection

Control parameters

Exposure Limits

Chemical name ACGIH TLV OSHA PEL NIOSH Nitric Acid TWA: 2 ppm TWA: 2 ppm IDLH: 25 ppm 7697-37-2 STEL: 4 ppm TWA: 5 mg/m3 TWA: 2 ppm (vacated) TWA: 2 ppm TWA: 5 mg/m3 (vacated) TWA: 5 mg/m3 STEL: 4 ppm (vacated) STEL: 4 ppm STEL: 10 mg/m3 (vacated) STEL: 10 mg/m3

Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies.

Appropriate engineering controls

Engineering controls Showers Eyewash stations Ventilation systems.

Individual protection measures, such as personal protective equipment

Eye/face protection Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Tight sealing safety goggles.

Hand protection Wear protective Neoprene™ gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear suitable gloves. Impervious gloves.

Skin and body protection Wear suitable protective clothing. Long sleeved clothing.

Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water.

General hygiene considerations Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Regular cleaning of equipment, work area and clothing is recommended.

9. Physical and chemical properties

Information on basic physical and chemical properties Physical state Liquid Appearance Liquid Color colorless Odor Odorless Odor threshold No information available

Property Values Remarks • Method pH No data available None known Melting point / freezing point No data available None known Initial boiling point and boiling rangeNo data available None known Flash point No data available None known Evaporation rate No data available None known Flammability No data available None known Flammability Limit in Air None known Upper flammability or explosive No data available limits Lower flammability or explosive No data available limits Vapor pressure No data available None known Relative vapor density No data available None known Relative density No data available None known Water solubility No data available None known Solubility(ies) No data available None known Partition coefficient No data available None known Autoignition temperature No data available None known Decomposition temperature None known Kinematic viscosity No data available None known Dynamic viscosity No data available None known

Other information Explosive properties No information available Oxidizing properties No information available Softening point No information available Molecular weight No information available VOC content No information available Liquid Density No information available

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Bulk density No information available

10. Stability and reactivity

Reactivity No information available.

Chemical stability Stable under normal conditions.

Possibility of hazardous reactions None under normal processing.

Conditions to avoid Exposure to air or moisture over prolonged periods.

Incompatible materials Oxidizing agent. Strong acids. Strong bases.

Hazardous decomposition products None known based on information supplied.

11. Toxicological information

Information on likely routes of exposure

Product Information

Inhalation Specific test data for the substance or mixture is not available.

Eye contact Specific test data for the substance or mixture is not available. Causes serious eye damage. May cause irreversible damage to eyes.

Skin contact Specific test data for the substance or mixture is not available. Causes skin irritation. (based on components).

Ingestion Specific test data for the substance or mixture is not available. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea.

Symptoms related to the physical, chemical and toxicological characteristics

Symptoms Redness. Burning. May cause blindness. May cause redness and tearing of the eyes.

Acute toxicity

Numerical measures of toxicity

The following values are calculated based on chapter 3.1 of the GHS document ATEmix (oral) 99,999.00 mg/kg ATEmix (dermal) 99,999.00 mg/kg

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

ATEmix (inhalation-gas) 99,999.00 ppm ATEmix (inhalation-dust/mist) 99,999.00 mg/l ATEmix (inhalation-vapor) 66.70 mg/l

Component Information Chemical name Oral LD50 Dermal LD50 Inhalation LC50 Nitric Acid - - = 2500 ppm ( Rat ) 1 h 7697-37-2 ATE (vapours) = 2.65 mg/L

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Skin corrosion/irritation Classification based on data available for ingredients. Causes skin irritation.

Serious eye damage/eye irritation Classification based on data available for ingredients. Causes burns. Causes serious eye damage.

Respiratory or skin sensitization No information available.

Germ cell mutagenicity No information available.

Carcinogenicity No information available.

Reproductive toxicity No information available.

STOT - single exposure No information available.

STOT - repeated exposure No information available.

Target organ effects Respiratory system, Eyes, Skin, Teeth.

Aspiration hazard No information available.

Other adverse effects No information available.

Interactive effects No information available.

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

12. Ecological information

Ecotoxicity The environmental impact of this product has not been fully investigated.

Persistence and degradability No information available.

Bioaccumulation There is no data for this product.

Component Information Chemical name Partition coefficient Nitric Acid -2.3 7697-37-2

Other adverse effects No information available.

13. Disposal considerations

Disposal methods

Waste from residues/unused Dispose of in accordance with local regulations. Dispose of waste in accordance with products environmental legislation.

Contaminated packaging Do not reuse empty containers.

California Hazardous Waste Status This product contains one or more substances that are listed with the State of California as a hazardous waste.

14. Transport information

DOT UN number or ID number UN3264 Extended proper shipping name Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) Transport hazard class(es) 8 Packing group III Reportable Quantity (RQ) (Nitric Acid: RQ (kg)= 454.00) Nitric Acid: RQ (lb)= 1000.00 Reportable quantity (kg) Nitric Acid: RQ (kg)= 10088.89 (calculated) Reportable quantity (lbs) Nitric Acid: RQ (lb)= 22222.00 (calculated)

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

Special Provisions IB3, T7, TP1, TP28 DOT Marine Pollutant NP Description UN3264, Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid), 8, III Emergency Response Guide 154 Number

TDG UN number or ID number UN3264 UN proper shipping name Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) Transport hazard class(es) 8 Packing group III Special Provisions 16 Marine pollutant NP Description UN3264, Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid), 8, III

MEX UN number or ID number UN3264 UN proper shipping name Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) Transport hazard class(es) 8 Packing group III Technical Name Nitric Acid Description UN3264, Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid), 8, III Special Provisions 223, 274

IATA UN number or ID number UN3264 UN proper shipping name Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) Transport hazard class(es) 8 Packing group III Technical Name Nitric Acid Description UN3264, Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid), 8, III Special Provisions A3, A803 ERG Code 8L

IMDG UN number or ID number UN3264 UN proper shipping name Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) Transport hazard class(es) 8 Packing group III EmS-No. F-A, S-B Special Provisions 223, 274 Marine pollutant NP Description UN3264, Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid), 8, III

15. Regulatory information

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

International Inventories

TSCA LGC, to the best of its ability, has confirmed that the chemical substances in this product are listed as “Active” in the EPA (Environmental Protection Agency) “TSCA Inventory Notification (Active-Inactive) Requirements Rule” (“the Final Rule”) of Feb 2019, as amended Feb 2021.”.

Chemical name CAS No. Inventory Listing Status Commercial Activity Designation Nitric Acid 7697-37-2 Present Active

DSL/NDSL Contact supplier for inventory compliance status. EINECS/ELINCS Contact supplier for inventory compliance status. ENCS Contact supplier for inventory compliance status. IECSC Contact supplier for inventory compliance status. KECI Contact supplier for inventory compliance status. PICCS Contact supplier for inventory compliance status. AIIC Contact supplier for inventory compliance status.

Legend: TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances AICS - Australian Inventory of Chemical Substances

US Federal Regulations

SARA 313

Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemical

or chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

Chemical name SARA 313 - Threshold Values % Nitric Acid - 7697-37-2 1.0

SARA 311/312 Hazard Categories Should this product meet EPCRA 311/312 Tier reporting criteria at 40 CFR 370, refer to Section 2 of this SDS for appropriate classifications.

CWA (Clean Water Act)

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

This product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42).

Chemical name CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants CWA - Hazardous Quantities Substances Nitric Acid 1000 lb - - X 7697-37-2

CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302).

Chemical name Hazardous Substances RQs Extremely Hazardous Reportable Quantity (RQ) Substances RQs Nitric Acid 1000 lb 1000 lb RQ 1000 lb final RQ 7697-37-2 RQ 454 kg final RQ

US State Regulations

California Proposition 65 This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

Chemical name New Jersey Massachusetts Pennsylvania Water - - X 7732-18-5 Nitric Acid X X X 7697-37-2

U.S. EPA Label Information

EPA Pesticide Registration Number Not applicable

16. Other information

NFPA Health hazards 3 Flammability 0 Instability 0 Special hazards - HMIS Health hazards 3 Flammability 0 Physical hazards 0 Personal protection X

Key or legend to abbreviations and acronyms used in the safety data sheet Legend Section 8: Exposure controls/personal protection

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SAFETY DATA SHEET This safety data sheet was created pursuant to the requirements of: OSHA HCS2012

5190-8456 - Gadolinium Standard: 1000 μg/mL Gd in Revision date 25-Jun-2024 5% HNO3 [500ml bottle]

TWA TWA (time-weighted average) STEL STEL (Short Term Exposure Limit) Ceiling Maximum limit value Sk* Skin designation

Key literature references and sources for data used to compile the SDS Agency for Toxic Substances and Disease Registry (ATSDR) U.S. Environmental Protection Agency ChemView Database European Food Safety Authority (EFSA) Environmental Protection Agency Acute Exposure Guideline Level(s) (AEGL(s)) U.S. Environmental Protection Agency Federal Insecticide, Fungicide, and Rodenticide Act U.S. Environmental Protection Agency High Production Volume Chemicals Food Research Journal Hazardous Substance Database International Uniform Chemical Information Database (IUCLID) Japan GHS Classification Australia National Industrial Chemicals Notification and Assessment Scheme (NICNAS) NIOSH (National Institute for Occupational Safety and Health) National Library of Medicine's ChemID Plus (NLM CIP) National Library of Medicine’s PubMed database (NLM PUBMED) U.S. National Toxicology Program (NTP) New Zealand's Chemical Classification and Information Database (CCID) Organization for Economic Co-operation and Development Environment, Health, and Safety Publications Organization for Economic Co-operation and Development High Production Volume Chemicals Program Organization for Economic Co-operation and Development Screening Information Data Set World Health Organization

Revision date 25-Jun-2024 Revision Note No information available. Disclaimer The information contained in this document is based on Agilent’s state of knowledge at the time of preparation. No warranty as to its accurateness, completeness or suitability for a particular purpose is expressed or implied. End of Safety Data Sheet

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