Gadolinium fluoride anhydrous SDS

Safety Data Sheet Page 1/5 per OSHA HazCom 2012 Printing date 11/24/2015 Reviewed on 04/27/2003

1 Identification

Product identifier Product name: Gadolinium fluoride anhydrous Stock number: 11292 CAS Number: 13765-26-9 EC number: 237-369-4 Relevant identified uses of the substance or mixture and uses advised against. Identified use: SU24 Scientific research and development Details of the supplier of the safety data sheet Manufacturer/Supplier: Alfa Aesar Thermo Fisher Scientific Chemicals, Inc. 30 Bond Street Ward Hill, MA 01835-8099 Tel: 800-343-0660 Fax: 800-322-4757 Email: tech@alfa.com www.alfa.com Information Department: Health, Safety and Environmental Department Emergency telephone number: During normal business hours (Monday-Friday, 8am-7pm EST), call (800) 343-0660. After normal business hours, call Carechem 24 at (866) 928-0789.

2 Hazard(s) identification

Classification of the substance or mixture in accordance with 29 CFR 1910 (OSHA HCS)

GHS06 Skull and crossbones

Acute Tox. 3 H301 Toxic if swallowed. Acute Tox. 3 H311 Toxic in contact with skin. Acute Tox. 3 H331 Toxic if inhaled. Hazards not otherwise classified No information known. Label elements GHS label elements The product is classified and labeled in accordance with 29 CFR 1910 (OSHA HCS) Hazard pictograms

GHS06

Signal word Danger Hazard statements H301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled. Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor/… P361 Take off immediately all contaminated clothing. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. WHMIS classification D1A - Very toxic material causing immediate and serious toxic effects

Classification system HMIS ratings (scale 0-4) (Hazardous Materials Identification System) HEALTH 2 Health (acute effects) = 2 FIRE 0 Flammability = 0 REACTIVITY 1 Physical Hazard = 1 Other hazards Results of PBT and vPvB assessment PBT: Not applicable. vPvB: Not applicable.

3 Composition/information on ingredients

Chemical characterization: Substances CAS# Description: 13765-26-9 Gadolinium fluoride anhydrous Identification number(s): EC number: 237-369-4

4 First-aid measures

Description of first aid measures General information Immediately remove any clothing soiled by the product. Remove breathing apparatus only after contaminated clothing has been completely removed. In case of irregular breathing or respiratory arrest provide artificial respiration. After inhalation In case of unconsciousness place patient stably in side position for transportation. Supply fresh air. If required, provide artificial respiration. Keep patient warm. (Contd. on page 2) USA

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Safety Data Sheet Page 2/5 per OSHA HazCom 2012 Printing date 11/24/2015 Reviewed on 04/27/2003 Product name: Gadolinium fluoride anhydrous

(Contd. of page 1) Seek immediate medical advice. After skin contact Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice. After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor. After swallowing Drink lots of water. Induce vomiting if patient is conscious. Do not induce vomiting; immediately call for medical help. Information for doctor Most important symptoms and effects, both acute and delayed No further relevant information available. Indication of any immediate medical attention and special treatment needed No further relevant information available.

5 Fire-fighting measures

Extinguishing media Suitable extinguishing agents Product is not flammable. Use fire-fighting measures that suit the surrounding fire. Special hazards arising from the substance or mixture If this product is involved in a fire, the following can be released: Hydrogen chloride (HCl) Metal oxide fume Advice for firefighters Protective equipment: Wear self-contained respirator. Wear fully protective impervious suit.

6 Accidental release measures

Personal precautions, protective equipment and emergency procedures Mount respiratory protective device. Wear protective equipment. Keep unprotected persons away. Ensure adequate ventilation Environmental precautions: Do not allow to enter sewers/ surface or ground water. Do not allow material to be released to the environment without proper governmental permits. Methods and material for containment and cleaning up: Dispose of contaminated material as waste according to section 13. Ensure adequate ventilation. Prevention of secondary hazards: No special measures required. Reference to other sections See Section 7 for information on safe handling See Section 8 for information on personal protection equipment. See Section 13 for disposal information.

7 Handling and storage

Handling Precautions for safe handling Thoroughly remove all dust particles. Keep container tightly sealed. Store in cool, dry place in tightly closed containers. Ensure good ventilation at the workplace. Open and handle container with care. Information about protection against explosions and fires: No information known. Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Store away from oxidizing agents. Do not store together with acids. Further information about storage conditions: Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

Additional information about design of technical systems: Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute. Control parameters Components with limit values that require monitoring at the workplace:

Fluorides (as F) mg/m3 ACGIH TLV 2.5 Austria MAK 2.5 Belgium TWA 2.5 Finland TWA 2.5 France TWA 2.5 Germany MAK 2.5 Hungary TWA 1; 2-STEL Netherlands MAC-K 3.5 Norway TWA 0.6 Poland TWA 1; 3-STEL Sweden NGV 2 Switzerland MAK-W 1.5; 3-KZG-W United Kingdom TWA 2.5 Russia TWA 2 Denmark TWA 2.5 USA PEL 2.5 Additional information: The exposure limits that were valid when the MSDS was created were used. No data (Contd. on page 3) USA

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Safety Data Sheet Page 3/5 per OSHA HazCom 2012 Printing date 11/24/2015 Reviewed on 04/27/2003 Product name: Gadolinium fluoride anhydrous

(Contd. of page 2) Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed. Keep away from foodstuffs, beverages and feed. Remove all soiled and contaminated clothing immediately. Wash hands before breaks and at the end of work. Store protective clothing separately. Avoid contact with the eyes and skin. Maintain an ergonomically appropriate working environment. Breathing equipment: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air. Use self-contained respiratory protective device in emergency situations. Recommended filter device for short term use: Filter P1 Protection of hands: Impervious gloves Protective gloves. Check protective gloves prior to each use for their proper condition. The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer. Penetration time of glove material (in minutes) Not determined Eye protection: Safety glasses Body protection: Protective work clothing.

9 Physical and chemical properties

Information on basic physical and chemical properties General Information Appearance: Form: Crystalline Color: White Odor: Odorless Odor threshold: Not determined. pH-value: Not applicable. Change in condition Melting point/Melting range: 1231 °C (2248 °F) Boiling point/Boiling range: Not determined Sublimation temperature / start: Not determined Flash point: Not applicable Flammability (solid, gaseous) Product is not flammable. Ignition temperature: Not determined Decomposition temperature: Not determined Auto igniting: Not determined. Danger of explosion: Product does not present an explosion hazard. Explosion limits: Lower: Not determined Upper: Not determined Vapor pressure: Not applicable. Density at 20 °C (68 °F): 7.047 g/cm³ (58.807 lbs/gal) Relative density Not determined. Vapor density Not applicable. Evaporation rate Not applicable. Solubility in / Miscibility with Water: Not determined Partition coefficient (n-octanol/water): Not determined. Viscosity: dynamic: Not applicable. kinematic: Not applicable. Other information No further relevant information available.

10 Stability and reactivity

Reactivity Contact with acids liberates very toxic gas. Chemical stability Stable under recommended storage conditions. Thermal decomposition / conditions to be avoided: Decomposition will not occur if used and stored according to specifications. Possibility of hazardous reactions Contact with acids liberates very toxic gas. Conditions to avoid No further relevant information available. Incompatible materials: Acids Hazardous decomposition products: Hydrogen fluoride Metal oxide fume

11 Toxicological information

Information on toxicological effects Acute toxicity: Toxic in contact with skin. Toxic if inhaled. Toxic if swallowed. Danger through skin absorption. LD/LC50 values that are relevant for classification: No data Skin irritation or corrosion: Irritant to skin and mucous membranes. Eye irritation or corrosion: Irritating effect. Sensitization: No sensitizing effects known. Germ cell mutagenicity: No effects known. Carcinogenicity: No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH. Reproductive toxicity: No effects known. Specific target organ system toxicity - repeated exposure: No effects known. Specific target organ system toxicity - single exposure: No effects known. Aspiration hazard: No effects known. (Contd. on page 4) USA

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Safety Data Sheet Page 4/5 per OSHA HazCom 2012 Printing date 11/24/2015 Reviewed on 04/27/2003 Product name: Gadolinium fluoride anhydrous

(Contd. of page 3) Subacute to chronic toxicity: Fluorides may cause salivation, nausea, vomiting, diarrhea and abdominal pain, followed by weakness, tremors, shallow respiration, convulsions and coma. May cause brain and kidney damage. Chronic fluoride poisoning can cause severe bone changes, loss of weight, anorexia, anemia and dental defects. Lanthanons can cause delayed blood clotting leading to hemorrhages. Exposure may also lead to sensitivity to heat, itching, increased awareness of odor and taste, and liver damage. Subacute to chronic toxicity: No effects known. Additional toxicological information: To the best of our knowledge the acute and chronic toxicity of this substance is not fully known. The substance is not subject to classification.

12 Ecological information

Toxicity Aquatic toxicity: No further relevant information available. Persistence and degradability No further relevant information available. Bioaccumulative potential No further relevant information available. Mobility in soil No further relevant information available. Additional ecological information: General notes: Do not allow material to be released to the environment without proper governmental permits. Do not allow undiluted product or large quantities to reach ground water, water course or sewage system. Avoid transfer into the environment. Results of PBT and vPvB assessment PBT: Not applicable. vPvB: Not applicable. Other adverse effects No further relevant information available.

13 Disposal considerations

Waste treatment methods Recommendation Consult state, local or national regulations to ensure proper disposal. Waste disposal key number according to the European Waste Catalogue: Contaminated salts: 06 03 05 Solid salts containing chlorides, fluorides and other halogenides Uncleaned packagings: Recommendation: Disposal must be made according to official regulations.

14 Transport information

UN-Number DOT, IMDG, IATA UN3288 UN proper shipping name DOT Toxic solid, inorganic, n.o.s. (Gadolinium fluoride anhydrous) IMDG, IATA TOXIC SOLID, INORGANIC, N.O.S. (Gadolinium fluoride anhydrous) Transport hazard class(es) DOT

Class 6.1 Toxic substances. Label 6.1 Class 6.1 (T5) Toxic substances Label 6.1 IMDG, IATA

Class 6.1 Toxic substances. Label 6.1 Packing group DOT, IMDG, IATA III Environmental hazards: Not applicable. Special precautions for user Warning: Toxic substances Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable. Transport/Additional information: DOT Marine Pollutant (DOT): No UN "Model Regulation": UN3288, Toxic solid, inorganic, n.o.s. (Gadolinium fluoride anhydrous), 6.1, III

15 Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements The product is classified and labeled in accordance with 29 CFR 1910 (OSHA HCS) Hazard pictograms

GHS06

Signal word Danger Hazard statements H301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled. Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. (Contd. on page 5) USA

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Safety Data Sheet Page 5/5 per OSHA HazCom 2012 Printing date 11/24/2015 Reviewed on 04/27/2003 Product name: Gadolinium fluoride anhydrous

(Contd. of page 4) P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor/… P361 Take off immediately all contaminated clothing. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. National regulations All components of this product are listed in the U.S. Environmental Protection Agency Toxic Substances Control Act Chemical substance Inventory. All components of this product are listed on the Canadian Non-Domestic Substances List (NDSL). SARA Section 313 (specific toxic chemical listings) Substance is not listed. California Proposition 65 Prop 65 - Chemicals known to cause cancer Substance is not listed. Prop 65 - Developmental toxicity Substance is not listed. Prop 65 - Developmental toxicity, female Substance is not listed. Prop 65 - Developmental toxicity, male Substance is not listed. Information about limitation of use: For use only by technically qualified individuals. Other regulations, limitations and prohibitive regulations Substance of Very High Concern (SVHC) according to the REACH Regulations (EC) No. 1907/2006. Substance is not listed. The conditions of restrictions according to Article 67 and Annex XVII of the Regulation (EC) No 1907/2006 (REACH) for the manufacturing, placing on the market and use must be observed. Substance is not listed. Annex XIV of the REACH Regulations (requiring Authorisation for use) Substance is not listed. Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

16 Other information

This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Employers should use this information only as a supplement to other information gathered by them, and should make independent judgement of suitability of this information to ensure proper use and protect the health and safety of employees. This information is furnished without warranty, and any use of the product not in conformance with this Material Safety Data Sheet, or in combination with any other product or process, is the responsibility of the user. Department issuing SDS: Global Marketing Department Date of preparation / last revision 11/24/2015 / 1 Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) IATA-DGR: Dangerous Goods Regulations by the "International Air Transport Association" (IATA) ICAO: International Civil Aviation Organization ICAO-TI: Technical Instructions by the "International Civil Aviation Organization" (ICAO) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) HMIS: Hazardous Materials Identification System (USA) WHMIS: Workplace Hazardous Materials Information System (Canada) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent vPvB: very Persistent and very Bioaccumulative ACGIH: American Conference of Governmental Industrial Hygienists (USA) OSHA: Occupational Safety and Health Administration (USA) NTP: National Toxicology Program (USA) IARC: International Agency for Research on Cancer EPA: Environmental Protection Agency (USA) USA

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