Gadolinium(III) fluoride SDS

SIGMA-ALDRICH sigma-aldrich.com SAFETY DATA SHEET Version 3.12 Revision Date 09/14/2017 Print Date 11/06/2018

1. PRODUCT AND COMPANY IDENTIFICATION

1.1 Product identifiers

Product name : Gadolinium(III) fluoride

Product Number : 432164 Brand : Aldrich

CAS-No. : 13765-26-9

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses : Laboratory chemicals, Synthesis of substances

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich 3050 Spruce Street SAINT LOUIS MO 63103 USA

Telephone : +1 800-325-5832 Fax : +1 800-325-5052

1.4 Emergency telephone number

Emergency Phone # : +1-703-527-3887 (CHEMTREC)

2. HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture

Not a hazardous substance or mixture.

2.2 GHS Label elements, including precautionary statements

Not a hazardous substance or mixture.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS

Weak hydrogen fluoride-releaser

3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances Formula : F3Gd Molecular weight : 214.25 g/mol CAS-No. : 13765-26-9 EC-No. : 237-369-4 Hazardous components Component Classification Concentration Gadolinium(III) fluoride 90 - 100 %

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4. FIRST AID MEASURES

4.1 Description of first aid measures

General advice Hydrofluoric (HF) acid burns require immediate and specialized first aid and medical treatment. Symptoms may be delayed up to 24 hours depending on the concentration of HF. After decontamination with water, further damage can occur due to penetration/absorption of the fluoride ion. Treatment should be directed toward binding the fluoride ion as well as the effects of exposure. Skin exposures can be treated with a 2.5% calcium gluconate gel repeated until burning ceases. More serious skin exposures may require subcutaneous calcium gluconate except for digital areas unless the physician is experienced in this technique, due to the potential for tissue injury from increased pressure. Absorption can readily occur through the subungual areas and should be considered when undergoing decontamination. Prevention of absorption of the fluoride ion in cases of ingestion can be obtained by giving milk, chewable calcium carbonate tablets or Milk of Magnesia to conscious victims. Conditions such as hypocalcemia, hypomagnesemia and cardiac arrhythmias should be monitored for, since they can occur after exposure.

If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration.

In case of skin contact First treatment with calcium gluconate paste.Wash off with soap and plenty of water.

In case of eye contact Flush eyes with water as a precaution.

If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water.

4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed No data available

5. FIREFIGHTING MEASURES

5.1 Extinguishing media

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture No data available

5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.

5.4 Further information No data available

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures Avoid dust formation. Avoid breathing vapours, mist or gas. For personal protection see section 8.

6.2 Environmental precautions No special environmental precautions required.

6.3 Methods and materials for containment and cleaning up Sweep up and shovel. Keep in suitable, closed containers for disposal.

6.4 Reference to other sections For disposal see section 13.

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7. HANDLING AND STORAGE

7.1 Precautions for safe handling Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place.

Keep in a dry place.

7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters

Components with workplace control parameters Component CAS-No. Value Control Basis parameters Gadolinium(III) 13765-26-9 TWA 2.500000 USA. Occupational Exposure Limits fluoride mg/m3 (OSHA) - Table Z-1 Limits for Air Contaminants Remarks CAS number varies with compound TWA 2.500000 USA. Occupational Exposure Limits mg/m3 (OSHA) - Table Z-2 Z37.28-1969 TWA 2.500000 USA. ACGIH Threshold Limit Values mg/m3 (TLV) Bone damage Fluorosis Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen varies TWA 2.500000 USA. ACGIH Threshold Limit Values mg/m3 (TLV) Bone damage Fluorosis Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen varies TWA 2.5 mg/m3 USA. Occupational Exposure Limits (OSHA) - Table Z-1 Limits for Air Contaminants CAS number varies with compound TWA 2.5 mg/m3 USA. ACGIH Threshold Limit Values (TLV) Bone damage Fluorosis Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen varies

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PEL 2.5 mg/m3 California permissible exposure limits for chemical contaminants (Title 8, Article 107)

Biological occupational exposure limits Component CAS-No. Parameters Value Biological Basis specimen

Gadolinium(III) 13765-26-9 Fluoride 3.0000 Urine ACGIH - Biological fluoride mg/g Exposure Indices (BEI) Remarks Prior to shift (16 hours after exposure ceases) Fluoride 10.0000 Urine ACGIH - Biological mg/g Exposure Indices (BEI) End of shift (As soon as possible after exposure ceases) Fluoride 2 mg/l Urine ACGIH - Biological Exposure Indices (BEI) Prior to shift (16 hours after exposure ceases) Fluoride 3 mg/l Urine ACGIH - Biological Exposure Indices (BEI) End of shift (As soon as possible after exposure ceases)

8.2 Exposure controls

Appropriate engineering controls General industrial hygiene practice.

Personal protective equipment

Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)

Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

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Respiratory protection Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure No special environmental precautions required.

9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties

a) Appearance Form: powder Colour: white

b) Odour No data available

c) Odour Threshold No data available

d) pH No data available

e) Melting point/freezing No data available point

f) Initial boiling point and No data available boiling range

g) Flash point Not applicable

h) Evaporation rate No data available

i) Flammability (solid, gas) No data available

j) Upper/lower No data available flammability or explosive limits

k) Vapour pressure No data available

l) Vapour density No data available

m) Relative density No data available

n) Water solubility No data available

o) Partition coefficient: n- No data available octanol/water

p) Auto-ignition No data available temperature

q) Decomposition No data available temperature

r) Viscosity No data available

s) Explosive properties No data available

t) Oxidizing properties No data available

9.2 Other safety information

No data available

10. STABILITY AND REACTIVITY

10.1 Reactivity No data available

10.2 Chemical stability Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions No data available

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10.4 Conditions to avoid No data available

10.5 Incompatible materials No data available

10.6 Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Hydrogen fluoride, gadolinium oxides Other decomposition products - No data available In the event of fire: see section 5

11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects

Acute toxicity No data available

Inhalation: No data available

Dermal: No data available

No data available

Skin corrosion/irritation No data available

Serious eye damage/eye irritation No data available

Respiratory or skin sensitisation No data available

Germ cell mutagenicity No data available

Carcinogenicity

IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.

Reproductive toxicity No data available

No data available

Specific target organ toxicity - single exposure No data available

Specific target organ toxicity - repeated exposure No data available

Aspiration hazard No data available

Additional Information RTECS: Not available

Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia.

Salivation, Nausea, Vomiting, Fever, Cough, Shortness of breath, Headache

12. ECOLOGICAL INFORMATION

12.1 Toxicity No data available

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12.2 Persistence and degradability No data available

12.3 Bioaccumulative potential No data available

12.4 Mobility in soil No data available

12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods

Product Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging Dispose of as unused product.

14. TRANSPORT INFORMATION

DOT (US) Not dangerous goods

IMDG Not dangerous goods

IATA Not dangerous goods

15. REGULATORY INFORMATION

SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards No SARA Hazards

Massachusetts Right To Know Components No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components CAS-No. Revision Date Gadolinium(III) fluoride 13765-26-9 2008-06-01

New Jersey Right To Know Components CAS-No. Revision Date Gadolinium(III) fluoride 13765-26-9 2008-06-01

California Prop. 65 Components This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

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16. OTHER INFORMATION

HMIS Rating Health hazard: 0 Chronic Health Hazard: Flammability: 0 Physical Hazard 0

NFPA Rating Health hazard: 0 Fire Hazard: 0 Reactivity Hazard: 0

Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

Preparation Information Sigma-Aldrich Corporation Product Safety – Americas Region 1-800-521-8956

Version: 3.12 Revision Date: 09/14/2017 Print Date: 11/06/2018

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